ArticleJournal of clinical microbiology2022
Diagnosing Fracture-Related Infections: Where Are We Now?
Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Incidence and risk factors of fracture-related infection after SIGN nailing of open femoral fractures in Ethiopia.Scientific reports · 2026Article
- From serum inflammatory markers to fluid, tissue, and molecular assays: current advances in the laboratory diagnosis of bone and joint infections.Frontiers in cellular and infection microbiology · 2026Review
- Predictive value of a preoperative computed tomography-derived perifracture soft-tissue envelope index for fracture-related infection after open reduction and internal fixation of tibial plateau fractures.Frontiers in medicine · 2026Article
- Sonication fluid cultures enhance pathogen identification in fracture-related-infection (FRI).Journal of bone and joint infection · 2026Article
- Predictors of complications after intramedullary nailing for lower extremity fractures in low-resource settings: a 10-year experience with the SIGN nail in Nigeria.Patient safety in surgery · 2025Article
- Bridging the Diagnostic Gap: Enhancing Orthopedic Infection Management through Laboratory Diagnostics in Nepal.JNMA; journal of the Nepal Medical Association · 2025Article
- Personalized Approaches to Diagnostic and Therapeutic Strategies in Periprosthetic Fracture-Related Infections (PFRIs): Case Series and Literature Review.Journal of personalized medicine · 2025Article
- Identifying risk factors for systemic complications following fracture-related infection.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Management of Fracture-Related Infection in Conflict Zones: Lessons Learned from Medical Missions to Gaza.Antibiotics (Basel, Switzerland) · 2024Article
- Antibacterial activities of titanium dioxide (TiOJournal of orthopaedic surgery and research · 2024Article
- [Diagnostic and therapeutic work-up of infected tibial nonunion].Unfallchirurgie (Heidelberg, Germany) · 2024Review
- Combination of albumin-to-globulin ratio and plasma fibrinogen is a sensitive tool for preoperative screening of infected nonunion in patients undergoing reoperation after open reduction and internal fixation: a retrospective study.Journal of orthopaedic surgery and research · 2022Article
- The State of Research in Fracture-Related Infection-A Bibliometric Analysis.Medicina (Kaunas, Lithuania) · 2022Review
- A bibliometric analysis of clinical research on fracture-related infection.BioMed research international · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate diagnosis of fracture-related infection (FRI) is critical for preventing poor outcomes such as loss of function or amputation. Due to the multiple variables associated with FRI, however, accurate diagnosis is challenging and complicated by a lack of standardized diagnostic criteria. Limitations with the current gold standard for diagnosis, which is routine microbiology culture, further complicate the diagnostic and management process. Efforts to optimize the process rely on a foundation of data derived from prosthetic joint infections (PJI), but differences in PJI and FRI make it clear that unique approaches for these distinct infections are required. A more concerted effort focusing on FRI has dominated more recent investigations and publications leading to a consensus definition by the American Orthopedics (AO) Foundation and the European Bone and Joint Infection Society (EBJIS). This has the potential to better standardize the diagnostic process, which will not only improve patient care but also facilitate more robust and reproducible research related to the diagnosis and management of FRI. The purpose of this minireview is to explore the consensus definition, describe the foundation of data supporting current FRI diagnostic techniques, and identify pathways for optimization of clinical microbiology-based strategies and data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.