Evidence map›Paper›PMID 34133822›Full record

SynthesisAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2022

Acceptability and uptake of HIV self-testing in emergency care settings: A systematic review and meta-analysis.

Adam R Aluisio, Rachel K Lim, Oliver Y Tang, Janet Sugut, John Kinuthia, Rose Bosire, Kate M Guthrie, David A Katz, Carey Farquhar, Michael J Mello

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Adam R AluisioDepartment of Emergency Medicine, Alpert Medical School of Brown University, Providence, USA.ORCID 0000-0001-7329-7333
Rachel K LimBrown University, Providence, USA.
Oliver Y TangAlpert Medical School of Brown University, Providence, USA.
Janet SugutDepartment of Accident and Emergency, Kenyatta National Hospital, Nairobi, Kenya.
John KinuthiaDepartment of Research & Programs, Kenyatta National Hospital, Nairobi, Kenya.
Rose BosireCenter for Public Health Research, Kenya Medical Research Institute (KEMRI, Nairobi, Kenya.
Kate M GuthrieDepartment of Psychiatry and Human Behavior, Alpert Medical School, Brown University, Providence, RI, USA.
David A KatzDepartment of Global Health, University of Washington, Seattle, USA.
Carey FarquharDepartment of Global Health, University of Washington, Seattle, USA.
Michael J MelloDepartment of Emergency Medicine, Alpert Medical School of Brown University, Providence, USA.
Brown University · USKenyatta National Hospital · KEUniversity of Washington · USKenya Medical Research Institute · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
HIV in Injury: eValuation of Self-Testing in African Emergency Care for the Injured (HIV AECI)K23AI145411 · NIAID · RHODE ISLAND HOSPITAL · PI ALUISIO, ADAM RUSSELL · 2020 to 2024
$974k
NIAID NIH HHS K23 AI145411NIAID NIH HHS P30 AI027757
6 · The paper itself

Abstract

backgroundEmergency departments (ED) interface with large numbers of patients that are often missed by conventional HIV testing approaches. ED-based HIV self-testing (HIVST) is an innovative engagement approach which has potential for testing gains among populations that have failed to be reached. This systematic review and meta-analysis evaluated acceptability and uptake of HIVST, as compared to standard provider-delivered testing approaches, among patients seeking care in ED settings.

methodsSix electronic databases were systematically searched (Dates: January 1990-May 2021). Reports with data on HIVST acceptability and/or testing uptake in ED settings were included. Two reviewers identified eligible records (κ= 0.84); quality was assessed using formalized criteria. Acceptability and testing uptake metrics were summarized, and pooled estimates were calculated using random-effects models with assessments of heterogeneity.

resultsOf 5773 records identified, seven met inclusion criteria. The cumulative sample was 1942 subjects, drawn from three randomized control trials (RCTs) and four cross-sectional studies. Four reports assessed HIVST acceptability. Pooled acceptability of self-testing was 92.6% (95% confidence interval [CI]: 88.0%-97.1%). Data from two RCTs demonstrated that HIVST significantly increased testing uptake as compared to standard programs (risk ratio [RR] = 4.41, 95% CI: 1.95-10.10, I

conclusionsAvailable data indicate that HIVST may be acceptable and may increase testing among patients seeking emergency care, suggesting that expanding ED-based HIVST programs could enhance HIV diagnosis. However, given the limitations of the reports, additional research is needed to better inform the evidence base.

Indexed as

Emergency Medical ServicesHIV InfectionsEmergency TreatmentHIV TestingHumansMass ScreeningSelf-Testing

Identifiers

PMID34133822
PMCPMC8674381
OpenAlexW3166239048

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.