ArticlePLoS neglected tropical diseases2021
Orthobunyaviruses in the Caribbean: Melao and Oropouche virus infections in school children in Haiti in 2014.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- (Re-)Emergence of Oropouche Virus (OROV) Infections: Systematic Review and Meta-Analysis of Observational Studies.Viruses · 2024Pooled it
- The Others: A Systematic Review of the Lesser-Known Arboviruses of the Insular Caribbean.Viruses · 2023Pooled it
- Emerging threat of Oropouche virus: Clinical features, experimental models, and virulence.Virulence · 2026Review
- Pediatric Arboviral Infections in Europe: Epidemiology, Clinical Features, Diagnosis and Prevention.Viruses · 2026Review
- Emergence and endemicity of arboviruses in Haiti: a review.IJID regions · 2026Review
- Article
- Characterization of arbovirus infections in patients within Haiti by screening discarded malaria rapid diagnostic test cassettes.PLoS neglected tropical diseases · 2026Article
- Article
- Phylogenomics and structural modelling feature accelerated evolution of Oropouche virus: 1955 to 2024.Virologica Sinica · 2025Article
- Oropouche Virus (OROV): Expanding Threats, Shifting Patterns, and the Urgent Need for Collaborative Research in Latin America.Viruses · 2025Article
- Re-emergence of Oropouche virus as a novel global threat.Current research in microbial sciences · 2025Review
- Oropouche Virus: An Emerging Neuroinvasive Arbovirus.Annals of neurology · 2024Review
- Oropouche Virus: An Emerging Orthobunyavirus.The Journal of general virology · 2024Review
- Oropouche Fever, Cuba, May 2024.Emerging infectious diseases · 2024Article
- OROPOUCHE VIRUS: MORE QUESTIONS THAN ANSWERS.Zoonoses (Shannon, Ireland) · 2024Article
- Diversity and Genetic Reassortment of Keystone Virus in Mosquito Populations in Florida.The American journal of tropical medicine and hygiene · 2023Article
- Genome Sequence of Genotype 1A Hepatovirus A Isolated from Plasma from a Haitian Child.Microbiology resource announcements · 2022Article
- Species Diversity, Habitat Distribution, and Blood Meal Analysis of Haematophagous Dipterans Collected by CDC-UV Light Traps in the Dominican Republic.Pathogens (Basel, Switzerland) · 2022Article
- An Overview of Neglected Orthobunyaviruses in Brazil.Viruses · 2022Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
We report the identification of two orthobunyaviruses, Melao virus (MELV) and Oropouche virus (OROV), in plasma specimens from Haitian children with acute febrile illness who presented during outbreaks caused by alpha- and flaviviruses in 2014. Heretofore not described as a human pathogen, MELV was isolated in cell culture from the plasma of five case patients. OROV RNA was detected in the plasma of an additional child, using an unbiased sequencing approach, with phylogenetic inference suggesting a close relationship with strains from Brazil. Abdominal pain was reported by four case patients with MELV infections, with lymphadenopathy noted in two cases. Our findings document the occurrence of these orthobunyaviruses within the Caribbean region and highlight the critical importance of surveillance with viral genome sequence analyses to identify outbreaks caused by these and other emerging viruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.