Evidence map›Paper›PMID 34133033›Full record

ArticleClinical cardiology2021

Ten-year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion.

Yong Kyun Kim, Chae Won Jang, Soon Ho Kwon, Jae Hoon Kim, Amir Lerman, Jang-Ho Bae

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. The Importance of Blood Inflammatory Parameters in the Assessment of Hemodynamically Significant Coronary Artery Stenosis.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
  2. Article
  3. Article
  4. Cardiac scoring systems, coronary artery disease and major adverse cardiovascular events: A scoping review.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2023
    Article
  5. Ten-year predictors of major adverse cardiovascular events in patients without angina.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yong Kyun KimDivision of Cardiology, Department of Internal Medicine, Konyang University Hospital, Daejeon, South Korea.ORCID https://orcid.org/0000-0002-7711-9662
Chae Won JangDivision of Cardiology, Department of Internal Medicine, Konyang University Hospital, Daejeon, South Korea.ORCID https://orcid.org/0000-0002-6476-710X
Soon Ho KwonDivision of Cardiology, Department of Internal Medicine, Konyang University Hospital, Daejeon, South Korea.ORCID https://orcid.org/0000-0002-3935-9892
Jae Hoon KimDivision of Cardiology, Department of Internal Medicine, Konyang University Hospital, Daejeon, South Korea.ORCID https://orcid.org/0000-0002-5380-6409
Amir LermanDepartment of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-9446-5313
Jang-Ho BaeDivision of Cardiology, Department of Internal Medicine, Konyang University Hospital, Daejeon, South Korea.ORCID https://orcid.org/0000-0001-9533-7527
Konyang University Hospital · KRMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe assessed the long-term clinical outcomes of an intermediate lesion (IL) according to the presence of a combined culprit lesion (CCL). HYPOTHESIS: Long-term clinical outcomes of IL may be affected by the presence of a CCL.

methodsAngiographic findings (n = 1096) and medical chart were reviewed. Patients with IL were divided into two groups: IL without CCL group (n = 383, 64.5%) and IL with CCL group (n = 211, 35.5%).

resultsThe major adverse cardiovascular events (MACE) in the IL with CCL group were significantly higher than those in the IL without CCL group (death: 12.3% vs. 7.0%, myocardial infarction: 3.3%vs. 0.5%, stroke: 6.6% vs. 2.6%, and revascularization [RVSC]: 25.1% vs. 7.6%) during a mean follow up period of 118.4 ± 5.5 months. IL related RVSC rate in the IL with CCL group was higher than that in the IL without CCL group (5.7% vs. 2.1%, p = 0.020). RVSC rate related to IL in total subjects was lower than that related to stented lesion (3.4% vs. 6.4%). The important predictors of total MACE in total subjects were the presence of CCL, IL percent diameter stenosis, hypertension, history of percutaneous coronary intervention, blood glucose and ejection fraction. The predictors of IL related RVSC were IL percent diameter stenosis and IL located in the right coronary artery.

conclusion10-year clinical outcomes of an IL (especially IL without CCL) were better than those of stented lesions. This study suggests that the IL can be safely followed up in sites that do not have ability to assess functional study.

Indexed as

Coronary StenosisMyocardial InfarctionPercutaneous Coronary InterventionCoronary AngiographyCoronary VesselsHumansTreatment Outcomecoronary artery stenosisintermediate coronary lesionprognosis

Identifiers

PMID34133033
PMCPMC8364722
OpenAlexW3167837174

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.