Evidence map›Paper›PMID 34132998›Full record

ArticleProbiotics and antimicrobial proteins2021

The Effect of Immunobiotic/Psychobiotic Lactobacillus acidophilus Strain INMIA 9602 Er 317/402 Narine on Gut Prevotella in Familial Mediterranean Fever: Gender-Associated Effects.

Astghik Z Pepoyan, Elya S Pepoyan, Lilit Galstyan, Natalya A Harutyunyan, Vardan V Tsaturyan, Tamas Torok, Alexey M Ermakov, Igor V Popov, Richard Weeks, Michael L Chikindas

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In one paragraph

Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Placebo-resistant gut bacteria:Frontiers in cellular and infection microbiology · 2024
    Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. GutWomen's health reports (New Rochelle, N.Y.) · 2024
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Astghik Z PepoyanDepartment of Food Safety and Biotechnology, Armenian National Agrarian University, Yerevan, Armenia. apepoyan@gmail.com.ORCID 0000-0002-1935-5341
Elya S PepoyanDepartment of Food Safety and Biotechnology, Armenian National Agrarian University, Yerevan, Armenia.
Lilit GalstyanYerevan State Medical University, Yerevan, Armenia.
Natalya A HarutyunyanDepartment of Food Safety and Biotechnology, Armenian National Agrarian University, Yerevan, Armenia.
Vardan V TsaturyanInternational Association for Human and Animals Health Improvement, Yerevan, Armenia.
Tamas TorokLawrence Berkeley National Laboratory, CA, Berkeley, USA.
Alexey M ErmakovCenter for Agrobiotechnology, Don State Technical University, Rostov-on-Don, Russia.
Igor V PopovCenter for Agrobiotechnology, Don State Technical University, Rostov-on-Don, Russia.
Richard WeeksHealth Promoting Naturals Laboratory, Rutgers State University, New Brunswick, NJ, USA.
Michael L ChikindasCenter for Agrobiotechnology, Don State Technical University, Rostov-on-Don, Russia.
Armenian National Agrarian University · AMDon State Technical University · RURutgers, The State University of New Jersey · USYerevan State Medical University · AMLawrence Berkeley National Laboratory · USYerevan State University · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Possible mechanisms involved in sex-dependent differences in the gut microbiota have a growing interest worldwide, but the effects of probiotics dependence on the gender of the host have remained outside of researchers' attention until now. Previously, our research data described gender-specific differences in the gut microbiota of Armenian Familial Mediterranean fever (FMF) patients. Taking into account the possible association of Prevotella spp. with depressive disorders, the aim of the current investigations was an evaluation of changes in the abundance of gut Prevotella of FMF patients in association with the patient's depression and gender. The differences between healthy and FMF diseased gut microbiota in terms of Prevotella abundance were revealed. In addition, the gender-dependent effects of immunobiotic/psychobiotic Narine on the abundance of gut Prevotella of FMF patients and patients' depression scores were shown by us in this study.

Indexed as

Familial Mediterranean FeverLactobacillus acidophilusPrevotellaProbioticsSex FactorsDepressionFemaleGastrointestinal MicrobiomeHumansMaleDepression levelFamilial Mediterranean feverGut microbiotaImmunobiotic NarinePatients’ genderPrevotellaPsychobiotic

Identifiers

PMID34132998
OpenAlexW3171068862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.