Evidence map›Paper›PMID 34132893›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021

Computed tomography associated radiation exposure in children with craniosynostosis.

Madeleine K Bruce, Aditya M Mittal, Darunee S Whitt, Lynda L Flom, Miles J Pfaff, Joseph E Losee, Jesse A Goldstein

Abstract read
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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. 3D Photography to Quantify the Severity of Metopic Craniosynostosis.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Madeleine K BruceUPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Aditya M MittalSchool of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Darunee S WhittOffice of Research Protections Radiation Safety, University of Pittsburgh, Pittsburgh, PA, USA.
Lynda L FlomUPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Miles J PfaffUPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Joseph E LoseeUPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Jesse A GoldsteinUPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA. jesse.goldstein@chp.edu.ORCID 0000-0002-5242-3844
Children's Hospital of Pittsburgh · USUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of computed tomography (CT) for diagnosis and surgical planning for craniosynostosis (CS) is well-established. The aim of this study was to quantify the cumulative medical radiation exposure from CT in patients with CS at a tertiary care children's hospital.

methodsMedical records of patients who presented at < 2 years of age and underwent surgical intervention for CS were examined for demographic information. Effective radiation dose (ERD) in mSv was calculated for each head CT. Descriptive statistics and ANOVA were performed. Mean ± SD is reported; p < 0.05 was considered significant.

resultsTwo hundred seventy-two patients met inclusion criteria: 241 nonsyndromic and 31 with syndromic diagnoses. For nonsyndromic patients, mean age at first head CT was 6.0 ± 4.9 months, mean number of CT scans obtained was 2.1 ± 1.1, and the mean total combined ERD was 9.1 ± 4.8 mSv. CT scans obtained at < 6 months of age had a significantly greater ERD than those obtained at > 6 months, 5.3 ± 1.9 versus 4.3 ± 1.4 mSv, respectively (p = 0.001).

conclusionsPatients with nonsyndromic CS undergo 2 CT scans on average related to their diagnosis, with a mean total ERD of 9.1 mSv; this is equivalent to 1.5 years of the average annual background radiation dose a person living in the USA will encounter from environmental radiation, medical exposures, and consumer products. A CT obtained at < 6 months is associated with a higher ERD; thus, we recommend delaying imaging from the initial presentation to the time of pre-operative planning when possible.

Indexed as

CraniosynostosesRadiation ExposureHeadHumansInfantRadiation DosageTomography, X-Ray ComputedComputed tomographyCraniosynostosisRadiation exposure

Identifiers

PMID34132893
OpenAlexW3170371470

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.