Evidence map›Paper›PMID 34132836›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

Does the mental health system provide effective coverage to people with schizophrenic disorder? A self-controlled case series study in Italy.

Giovanni Corrao, Angelo Barbato, Barbara D'Avanzo, Teresa Di Fiandra, Lucia Ferrara, Andrea Gaddini, Matteo Monzio Compagnoni, Alessio Saponaro, Salvatore Scondotto, Valeria D Tozzi and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Giovanni CorraoNational Centre for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy.
Angelo BarbatoUnit for Quality of Care and Rights Promotion in Mental Health, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy.
Barbara D'AvanzoUnit for Quality of Care and Rights Promotion in Mental Health, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy.
Teresa Di FiandraGeneral Directorate for Health Prevention, Ministry of Health, Rome, Italy.
Lucia FerraraCentre of Research on Health and Social Care Management, SDA Bocconi School of Management, Bocconi University, Milan, Italy.
Andrea GaddiniAgency for Public Health, Lazio Region, Rome, Italy.
Matteo Monzio CompagnoniNational Centre for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy. matteo.monziocompagnoni@unimib.it.ORCID http://orcid.org/0000-0002-2105-4572
Alessio SaponaroGeneral Directorate of Health and Social Policies, Emilia-Romagna Region, Bologna, Italy.
Salvatore ScondottoNational Centre for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy.
Valeria D TozziCentre of Research on Health and Social Care Management, SDA Bocconi School of Management, Bocconi University, Milan, Italy.
Flavia CarleNational Centre for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy.
Antonio Lora *National Centre for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy.
“QUADIM project”, “Monitoring, assessing care pathways (M. A. P.)” working groups of the Italian Ministry of Health
Agenzia Regionale per la Protezione Ambientale del Piemonte · ITUniversity of Milano-Bicocca · ITAziende Socio Sanitarie Territoriali di LeccoBocconi University · ITRegione Siciliana · ITMario Negri Institute for Pharmacological Research · ITMinistero della Salute · ITAgenzia Sanitaria e Sociale Regionale · ITMarche Polytechnic University · IT

Funding

Ministero della Salute F52F16001420001Ministero della Salute H45E17000490001
6 · The paper itself

Abstract

purposeTo measure indicators of timeliness and continuity of treatments on patients with schizophrenic disorder in 'real-life' practice, and to validate them through their relationship with relapse occurrences.

methodsThe target population was from four Italian regions overall covering 22 million beneficiaries of the NHS (37% of the entire Italian population). The cohort included 12,054 patients newly taken into care for schizophrenic disorder between January 2015 and June 2016. The self-controlled case series (SCCS) design was used to estimate the incidence rate ratio of relapse occurrences according to mental healthcare coverage.

resultsPoor timeliness (82% and 33% of cohort members had not yet started treatment with psychosocial interventions and antipsychotic drug therapy within the first year after they were taken into care) and continuity (27% and 23% of patients were persistent with psychosocial interventions, and antipsychotic drug therapy within the first 2 years after starting the specific treatment) were observed. According to SCCS design, 4794 relapses occurred during 9430 PY (with incidence rate of 50.8 every 100 PY). Compared with periods not covered by mental healthcare, those covered by psychosocial intervention alone, antipsychotic drugs alone and by psychosocial intervention and antipsychotic drugs together were, respectively, associated with relapse rate reductions of 28% (95% CI 4-46%), 24% (17-30%) and 44% (32-53%).

conclusionHealthcare administrative data may contribute to monitor and to assess the effectiveness of a mental health system. Persistent use of both psychosocial intervention and antipsychotic drugs reduces risk of severe relapse.

Indexed as

Antipsychotic AgentsSchizophreniaCohort StudiesHumansMental HealthResearch DesignAntipsychotic AgentsEffective coverageHealthcare utilization databaseMental healthcareReal-worldSchizophrenic disorderSelf-controlled case series

Identifiers

PMID34132836
PMCPMC8934324
OpenAlexW3171223029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.