Evidence map›Paper›PMID 34132571›Full record

ArticleJournal of virology2021

Capsid Proteins Are Necessary for Replication of a Parvovirus.

Thomas Labadie, Deborah Garcia, Doriane Mutuel, Mylène Ogliastro, Guillaume Cambray

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Thomas LabadieCentre de Biologie Structurale (CBS), University of Montpellier, INSERM U1054, CNRS UMR5048, Montpellier, France.
Deborah GarciaDiversité des Génomes et Interactions Microorganismes Insectes (DGIMI), University of Montpellier, INRAE UMR 1333, Montpellier, France.
Doriane MutuelDiversité des Génomes et Interactions Microorganismes Insectes (DGIMI), University of Montpellier, INRAE UMR 1333, Montpellier, France.
Mylène OgliastroDiversité des Génomes et Interactions Microorganismes Insectes (DGIMI), University of Montpellier, INRAE UMR 1333, Montpellier, France.
Guillaume CambrayDiversité des Génomes et Interactions Microorganismes Insectes (DGIMI), University of Montpellier, INRAE UMR 1333, Montpellier, France.
Université de Montpellier · FRCentre National de la Recherche Scientifique · FR

Funding

CNRS-INSERM ATIP-AvenirEC | H2020 | H2020 Priority Excellent Science | H2020 Marie Skłodowska-Curie Actions (MSCA) 660212INRAE SPE
6 · The paper itself

Abstract

Despite tight genetic compression, viral genomes are often organized into functional gene clusters, a modular structure that might favor their evolvability. This has greatly facilitated biotechnological developments such as the recombinant adeno-associated virus (AAV) systems for gene therapy. Following this lead, we endeavored to engineer the related insect parvovirus Junonia coenia densovirus (JcDV) to create addressable vectors for insect pest biocontrol. To enable safer manipulation of capsid mutants, we translocated the nonstructural (

Indexed as

Genome, ViralVirus Replication3' Untranslated RegionsAnimalsCapsid ProteinsDensovirusGenetic VectorsParvoviridae InfectionsPest Control, BiologicalSpodopteraViral Nonstructural Proteins3' Untranslated RegionsCapsid ProteinsViral Nonstructural Proteinscapsiddensovirusreplicationsynthetic biology

Identifiers

PMID34132571
PMCPMC8354234
OpenAlexW3170485974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.