Evidence map›Paper›PMID 34132463›Full record

ArticleJournal of cellular and molecular medicine2021

Next-generation sequencing in two cases of de novo acute basophilic leukaemia.

Takuya Shimizu, Tadakazu Kondo, Yasuhito Nannya, Mizuki Watanabe, Toshio Kitawaki, Takero Shindo, Masakatsu Hishizawa, Kouhei Yamashita, Seishi Ogawa, Akifumi Takaori-Kondo

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Takuya ShimizuDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-1827-8081
Tadakazu KondoDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-8959-6271
Yasuhito NannyaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mizuki WatanabeDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-4030-4653
Toshio KitawakiDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takero ShindoDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Masakatsu HishizawaDepartment of Hematology, Kyoto-Katsura Hospital, Kyoto, Japan.
Kouhei YamashitaDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Seishi OgawaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Akifumi Takaori-KondoDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kyoto University · JPKyoto Katsura Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute basophilic leukaemia (ABL) is a rare subtype of acute myeloid leukaemia (AML); therefore, few data are available about its biology. Herein, we analysed two ABL patients using flow cytometry and next-generation sequencing (NGS). Two cell populations were detected by flow cytometry in both patients. In Case no. 1, blasts (CD34

Indexed as

MutationAgedAntigens, CD34BasophilsDioxygenasesDNA-Binding ProteinsHigh-Throughput Nucleotide SequencingHumansInterleukin-3 Receptor alpha SubunitLeukemia, Basophilic, AcuteMaleMiddle AgedNucleophosminProto-Oncogene Proteins c-kitSequence Analysis, DNATumor Suppressor Protein p53Antigens, CD34DioxygenasesDNA-Binding ProteinsInterleukin-3 Receptor alpha SubunitNPM1 protein, humanNucleophosminProto-Oncogene Proteins c-kitTET2 protein, humanTumor Suppressor Protein p53acute basophilic leukaemiagemtuzumab ozogamicinnext-generation sequencing

Identifiers

PMID34132463
PMCPMC8278069
OpenAlexW3172254717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.