Evidence map›Paper›PMID 34132429›Full record

SynthesisPhytotherapy research : PTR2021

Promising traditional Indian medicinal plants for the management of novel Coronavirus disease: A systematic review.

Rahul Soloman Singh, Ashutosh Singh, Harpinder Kaur, Gitika Batra, Phulen Sarma, Hardeep Kaur, Anusuya Bhattacharyya, Amit Raj Sharma, Subodh Kumar, Sujata Upadhyay and 4 more

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Phytotherapy research : PTR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Phytomedicines explored underSouth African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2022
    Review
  11. Review
  12. Phytocompounds and COVID-19: Two years of knowledge.Phytotherapy research : PTR · 2022
    Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Rahul Soloman SinghDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0002-3532-0018
Ashutosh SinghDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Harpinder KaurDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Gitika BatraDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Phulen SarmaDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Hardeep KaurDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Anusuya BhattacharyyaDepartment of Ophthalmology, Government Medical College & Hospital, Sector-32, Chandigarh, India.
Amit Raj SharmaDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Subodh KumarDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sujata UpadhyayDepartment of Physilogy, Dr. Harvansh Singh Judge Institute of Dental Sciences & Hospital, Panjab University, Chandigarh, India.
Vinod TiwariDepartment of Pharmaceutical Engineering & Technology, Indian Institute of Technology, Banaras Hindu University Campus, Varanasi, India.
Pramod AvtiDepartment of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ajay PrakashDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0002-3487-8482
Bikash MedhiDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0002-4017-641X
Post Graduate Institute of Medical Education and Research · INGovernment Medical College and Hospital · INIndian Institute of Technology Indore · INPanjab University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional Indian medical practices (Ayurveda, Siddha, Unani, and homeopathy) are a vast reservoir of knowledge about medicinal plants. The promising pharmacological properties of these plants have paved the way for developing therapy against novel Coronavirus (CoV) infection. The current review will summarize published works of literature on the effects of traditional Indian medicinal plants against acute respiratory infection (COVID-19, SARS, Influenza, and Respiratory syncytial virus infection) and registered clinical trials of traditional Indian herbal medicines in COVID-19. The current study aims to comprehensively evaluate the data of traditional Indian medicinal plants to warrant their use in COVID-19 management. PubMed, Embase, and Cochrane databases were searched along with different clinical trial databases. A total of 22 relevant traditional Indian medicinal plants (35 relevant studies) were included in the current study having potential antiviral properties against virus-induced respiratory illness along with promising immunomodulatory and thrombolytic properties. Further, 36 randomized and nonrandomized registered clinical trials were also included that were aimed at evaluating the efficacy of herbal plants or their formulations in COVID-19 management. The antiviral, immunomodulatory, and thrombolytic activities of the traditional Indian medicinal plants laid down a strong rationale for their use in developing therapies against SARS-CoV-2 infection. The study identified some important potential traditional Indian medicinal herbs such as Ocimum tenuiflorum, Tinospora cordifolia, Achyranthes bidentata, Cinnamomum cassia, Cydonia oblonga, Embelin ribes, Justicia adhatoda, Momordica charantia, Withania somnifera, Zingiber officinale, Camphor, and Kabusura kudineer, which could be used in therapeutic strategies against SARS-CoV-2 infection.

Indexed as

COVID-19 Drug TreatmentMedicine, AyurvedicPlants, MedicinalHumansIndiaPlant PreparationsRandomized Controlled Trials as TopicPlant PreparationsAyurvedic medicineCOVID-19homeopathymedicinal plantsrespiratory syncytial virus infectionsSARS virusUnani medicine

Identifiers

PMID34132429
PMCPMC8441711
OpenAlexW3171866528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.