Evidence map›Paper›PMID 34132393›Full record

ArticleBritish journal of haematology2021

Immature platelets as a biomarker for disease severity and mortality in COVID-19 patients.

Daniel Welder, Haekyung Jeon-Slaughter, Bilal Ashraf, Sung-Hee Choi, Weina Chen, Ibrahim Ibrahim, Taha Bat

Abstract read
In one paragraph

Article in British journal of haematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Immunity and Coagulation in COVID-19.International journal of molecular sciences · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Platelets as a Gauge of Liver Disease Kinetics?International journal of molecular sciences · 2022
    Review
  8. Role of Biomarkers and Its Trend to Predict the Outcome of COVID-19 Patients: A Retrospective Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Platelet Subtypes in Inflammatory Settings.Frontiers in cardiovascular medicine · 2022
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Immature platelets in COVID-19 infection.British journal of haematology · 2021
    Article
  19. Immature Platelets and Platelet Reactivity in Patients with COVID-19.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Daniel WelderDepartment of Pathology, Hematopathology Section, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Haekyung Jeon-SlaughterDepartment of Internal Medicine, VA North Texas Health Care System, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Bilal AshrafDepartment of Internal Medicine, Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Sung-Hee ChoiDepartment of Internal Medicine, VA North Texas Health Care System and Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Weina ChenDepartment of Pathology, Hematopathology Section, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-5638-4371
Ibrahim IbrahimDepartment of Internal Medicine, Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Taha BatDepartment of Internal Medicine, Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-8810-1038

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19, caused by SARS-CoV-2, is a contagious life-threatening viral disease that has killed more than three million people worldwide to date. Attempts have been made to identify biomarker(s) to stratify disease severity and improve treatment and resource allocation. Patients with SARS-COV-2 infection manifest with a higher inflammatory response and platelet hyperreactivity; this raises the question of the role of thrombopoiesis in COVID-19 infection. Immature platelet fraction (IPF, %) and immature platelet counts (IPC, ×10

Indexed as

ThrombopoiesisAgedBlood PlateletsCOVID-19FemaleHospitalizationHumansIntensive Care UnitsMaleMiddle AgedPlatelet CountSARS-CoV-2Severity of Illness IndexbiomarkerCOVID-19immature plateletIPFreticulated platelets

Identifiers

PMID34132393
PMCPMC8444912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.