Evidence map›Paper›PMID 34132259›Full record

ReviewChemical Society reviews2021

Tools and methods for circular dichroism spectroscopy of proteins: a tutorial review.

A J Miles, Robert W Janes, B A Wallace

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed.

  1. NA-CDQuant: Quantitative spectral analysis of nucleic acid structure by circular dichroism spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Twisting light the Weyl way.Nature materials · 2026
    Article
  3. Article
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  5. Article
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  7. Article
  8. Guidelines for Comparing Circular Dichroism Spectroscopy and Molecular Dynamics Simulations for Biomolecules.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Article
  9. Review
  10. EnterohemorrhagicACS omega · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Characterization of the interaction between tartrazine andCurrent research in food science · 2026
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A J MilesInstitute of Structural and Molecular Biology, Birkbeck University of London, London WC1E 7HX, UK. b.wallace@mail.cryst.bbk.ac.uk.
Robert W Janes
B A Wallace

Funding

Biotechnology and Biological Sciences Research Council BB/F010346/1
6 · The paper itself

Abstract

Circular dichroism (CD) spectroscopy is a widely-used method in biochemistry, structural biology and pharmaceutical chemistry. More than 24 000 papers published in the past decade have included CD characterisations of proteins; many of those studies have also included other complementary chemical, biophysical, and computational chemistry methods. This tutorial review describes the background to the technique of CD spectroscopy and good practice methods for high quality data collection. It specifically focuses on both established and new methods and tools available for experimental design and interpretation, data processing, visualisation, analysis, validation, archiving, and accession, including tools developed to enhance the complementarity of this method with other structural and chemical biology studies.

Indexed as

BiochemistryCircular DichroismHumansProteinsProteins

Identifiers

PMID34132259
PMCPMC8328188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.