Evidence map›Paper›PMID 34132195›Full record

ArticleeLife2021

Single-cell RNA-seq analysis reveals penaeid shrimp hemocyte subpopulations and cell differentiation process.

Keiichiro Koiwai, Takashi Koyama, Soichiro Tsuda, Atsushi Toyoda, Kiyoshi Kikuchi, Hiroaki Suzuki, Ryuji Kawano

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 97 citations in OpenAlex.

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  5. Chromosome-scale genome assembly of Malcolmia littorea using long-read sequencing and single-pollen genotyping technologies.DNA research : an international journal for rapid publication of reports on genes and genomes · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Keiichiro KoiwaiDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei, Japan.ORCID 0000-0002-8890-8229
Takashi KoyamaFisheries Laboratory, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Hamamatsu, Japan.ORCID 0000-0001-7140-7244
Soichiro TsudabitBiome Inc, Shinjuku, Japan.
Atsushi ToyodaAdvanced Genomics Center, National Institute of Genetics, Mishima, Japan.ORCID 0000-0002-0728-7548
Kiyoshi KikuchiFisheries Laboratory, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Hamamatsu, Japan.
Hiroaki SuzukiDepartment of Precision Mechanics, Faculty of Science and Engineering, Chuo University, Bunkyo, Japan.ORCID 0000-0002-8899-0955
Ryuji KawanoDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei, Japan.ORCID 0000-0001-6523-0649
Chuo University · JPNagasaki University · JPNational Institute of Genetics · JPThe University of Tokyo · JPTokyo University of Agriculture and Technology · JPTokyo University of Marine Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crustacean aquaculture is expected to be a major source of fishery commodities in the near future. Hemocytes are key players of the immune system in shrimps; however, their classification, maturation, and differentiation are still under debate. To date, only discrete and inconsistent information on the classification of shrimp hemocytes has been reported, showing that the morphological characteristics are not sufficient to resolve their actual roles. Our present study using single-cell RNA sequencing revealed six types of hemocytes of

Indexed as

HemocytesPenaeidaeAnimalsArthropod ProteinsCell DifferentiationFemaleRNA-SeqSingle-Cell AnalysisArthropod Proteinscell biologycell differentiationcrustaceandevelopmental biologyhemocytesmarsupenaeus japonicusnon-model organismsscRNA-seq

Identifiers

PMID34132195
PMCPMC8266392
OpenAlexW3168572674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.