Evidence map›Paper›PMID 34132064›Full record

ArticleVeterinary medicine and science2022

Application of the gamma-interferon assay to determine the prevalence of bovine tuberculosis in slaughter livestock at abattoirs in Gauteng, South Africa.

Vuyokazi E Mareledwane, Abiodun A Adesiyun, Peter N Thompson, Tiny M Hlokwe

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Absence of Tuberculosis-CausingInternational journal of microbiology · 2024
    Article
  5. Transboundary and emerging diseases · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Vuyokazi E MareledwaneDepartment of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.ORCID 0000-0003-2443-3874
Abiodun A AdesiyunDepartment of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.ORCID 0000-0001-9470-9421
Peter N ThompsonDepartment of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
Tiny M HlokweDiagnostic Service Programme, Agricultural Research Council-Onderstepoort Veterinary Research, Onderstepoort, South Africa.
Onderstepoort Veterinary Academic Hospital · ZAOnderstepoort Veterinary Institute · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBovine tuberculosis (bTB) is a zoonotic disease with great economic impact estimated at billions of dollars annually worldwide. Meat inspection represents a long-standing form of disease surveillance that serves both food safety and animal health. The objective of this study was to determine the prevalence of bTB in livestock at abattoirs using a cell-mediated immune (CMI) assay, the gamma interferon (IFN-γ) assay. This cross-sectional study was conducted at selected abattoirs (low-throughput, high-throughput and rural/informal) in Gauteng province, where animals were also subjected to routine meat inspection.

resultsA total of 410 fresh blood samples were collected from slaughter livestock (369 cattle and 41 sheep) from 15 abattoirs, and analysed using Bovigam

conclusionThe detection of bTB reactor cattle in our study clearly shows the limitation of disease surveillance using a meat inspection approach, as all the 410 slaughter animals sampled had passed visual abattoir inspection and been classified as bTB-free. Our findings therefore emphasize the risk of zoonotic transmission of bTB to abattoir workers and potential food safety hazard to consumers. Furthermore, our study highlights the potential for the use of the IFN-γ assay to reduce this risk.

Indexed as

Cattle DiseasesSheep DiseasesTuberculosis, BovineAbattoirsAnimalsCattleCross-Sectional StudiesFemaleInterferon-gammaLivestockMalePrevalenceSheepSouth AfricaInterferon-gammaabattoirsbovine tuberculosiscattlegamma interferon assayzoonosis

Identifiers

PMID34132064
PMCPMC9677385
OpenAlexW3172544124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.