Evidence map›Paper›PMID 34131911›Full record

ReviewJournal of anatomy2022

Peripheral glia diversity.

Chelsey B Reed, M Laura Feltri, Emma R Wilson

Abstract readReview
In one paragraph

Review in Journal of anatomy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Junctions in Jeopardy: the neuromuscular junction is a selective pathological target in Charcot-Marie-Tooth disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  5. Review
  6. Glia of the heart's nervous system.Nature reviews. Neuroscience · 2025
    Review
  7. Review
  8. Gene therapy ameliorates neuromuscular pathology in CLN3 disease.Acta neuropathologica communications · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Cell Heterogeneity and Variability in Peripheral Nerve after Injury.International journal of molecular sciences · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chelsey B ReedHunter James Kelly Research Institute, Jacobs School of Medicine and Biomedical Sciences State, University of New York at Buffalo, Buffalo, New York, USA.
M Laura FeltriHunter James Kelly Research Institute, Jacobs School of Medicine and Biomedical Sciences State, University of New York at Buffalo, Buffalo, New York, USA.
Emma R WilsonHunter James Kelly Research Institute, Jacobs School of Medicine and Biomedical Sciences State, University of New York at Buffalo, Buffalo, New York, USA.ORCID 0000-0002-8069-0173

Funding

Laminin Receptors and Signals in Schwann CellsR01NS045630 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI SIM, FRASER JAMES · 2003 to 2024
$5.9M
The prohibitin family and their function in myelination and axonal healthR01NS100464 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI FELTRI, M. LAURA · 2016 to 2020
$1.7M
FeltriNINDS NIH HHS R01 NS045630NINDS NIH HHS R01 NS100464Wrabetz
6 · The paper itself

Abstract

Recent years have seen an evolving appreciation for the role of glial cells in the nervous system. As we move away from the typical neurocentric view of neuroscience, the complexity and variability of central nervous system glia is emerging, far beyond the three main subtypes: astrocytes, oligodendrocytes, and microglia. Yet the diversity of the glia found in the peripheral nervous system remains rarely discussed. In this review, we discuss the developmental origin, morphology, and function of the different populations of glia found in the peripheral nervous system, including: myelinating Schwann cells, Remak Schwann cells, repair Schwann cells, satellite glia, boundary cap-derived glia, perineurial glia, terminal Schwann cells, glia found in the skin, olfactory ensheathing cells, and enteric glia. The morphological and functional heterogeneity of glia found in the periphery reflects the diverse roles the nervous system performs throughout the body. Further, it highlights a complexity that should be appreciated and considered when it comes to a complete understanding of the peripheral nervous system in health and disease.

Indexed as

NeurogliaSchwann CellsAstrocytesCentral Nervous SystemPeripheral Nervesboundary cap-derivedcutaneousensheathingentericolfactoryperineurialperisynapticsatelliteSchwann cellsterminal

Identifiers

PMID34131911
PMCPMC8671569

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.