Evidence map›Paper›PMID 34131778›Full record

ArticleHeart and vessels2022

Changes in prognostic nutritional index during hospitalization and outcomes in patients with acute heart failure.

Takayuki Kawata, Atsushi Ikeda, Hiroshi Masuda, Shunsuke Komatsu

Abstract read
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. The ability of the prognostic nutritional index to predict short-term mortality in geriatric acute heart failure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Prognostic Nutritional Index (PNI) as a Predictor in Patients with Metabolic Syndrome and Heart Failure.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
  10. Article
  11. Significance of Preoperative Prognostic Nutritional Index in the Perioperative Management of Gastric Cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Takayuki KawataDepartment of Cardiovascular Medicine, Sassa General Hospital, 4-24-15, Tanashicho, Nishi Tokyo-City, Tokyo, 188-0011, Japan. dqh07724@nifty.ne.jp.
Atsushi IkedaDepartment of Cardiovascular Medicine, Sassa General Hospital, 4-24-15, Tanashicho, Nishi Tokyo-City, Tokyo, 188-0011, Japan.
Hiroshi MasudaDepartment of Cardiovascular Medicine, Sassa General Hospital, 4-24-15, Tanashicho, Nishi Tokyo-City, Tokyo, 188-0011, Japan.
Shunsuke KomatsuDepartment of Cardiovascular Medicine, Sassa General Hospital, 4-24-15, Tanashicho, Nishi Tokyo-City, Tokyo, 188-0011, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the prognostic nutritional index (PNI) is reported as a prognosticator in patients with heart failure (HF), that is evaluated usually on one occasion, and any changes in PNI during hospitalization are not considered. This study aimed to assess between changes in the PNI during hospitalization and outcomes in patients with acute HF. We enrolled 141 patients (median age, 84 years, 75 male) admitted to our hospital for the treatment of acute HF. The PNI was calculated on admission and at discharge based on the original report. According to the PNI change during hospitalization, patients were classified as either improved (PNI at discharge ≥ PNI on admission) or deteriorated (PNI at discharge < PNI on admission). Primary outcomes were all-cause death or unplanned hospitalization due to HF within the first year. Forty-nine events occurred (19 deaths, 30 HF hospitalizations). The event-free survival rate determined by Kaplan-Meier analysis was significantly higher in patients in the improved group (log-rank test, P < 0.0001), regardless of the PNI value on admission. Multivariate analysis showed that younger age (HR 1.06, 95% CI 1.01-1.11, P = 0.016), higher body mass index (HR 0.90, 95% CI 0.82-0.98, P = 0.021) and the PNI in the improved group (HR 0.30, 95% CI 0.14-0.57, P = 0.0006) were independently associated with favorable outcomes. In conclusion, changes in nutritional status during hospitalization, evaluated using the PNI on admission and at discharge, were independently associated with 1-year outcomes in patients with acute HF.

Indexed as

Heart FailureNutrition AssessmentAged, 80 and overFemaleHospitalizationHumansMaleNutritional StatusPrognosisRetrospective StudiesRisk FactorsAcute heart failurePrognosisPrognostic nutritional index

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.