Evidence map›Paper›PMID 34131585›Full record

ArticleTransplantation direct2021

Kidney Transplant Recipient Attitudes Toward a SARS-CoV-2 Vaccine.

Michael T Ou, Brian J Boyarsky, Laura B Zeiser, Teresa Po-Yu Chiang, Jake Ruddy, Sarah E Van Pilsum Rasmussen, Jennifer Martin, Jennifer St Clair Russell, Christine M Durand, Robin K Avery and 5 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Effect of ArtemiC in patients with COVID-19: A Phase II prospective study.Journal of cellular and molecular medicine · 2022
    Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Kidney transplant recipients' attitudes toward COVID-19 vaccination and barriers and enablers to vaccine acceptance.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Article
  9. Article
  10. Article
  11. Kidney transplantation and patients who decline SARS-CoV-2 vaccination: an ethical framework.Transplant international : official journal of the European Society for Organ Transplantation · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Michael T OuDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Brian J BoyarskyDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Laura B ZeiserDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Teresa Po-Yu ChiangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Jake RuddyDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Sarah E Van Pilsum RasmussenDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Jennifer MartinNational Kidney Foundation, New York, NY.
Jennifer St Clair RussellNational Kidney Foundation, New York, NY.
Christine M DurandDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Robin K AveryDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
William A WerbelDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Matthew CooperMedstar Georgetown Transplant Institute, Washington, DC.
Allan B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Jacqueline M Garonzik-WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Johns Hopkins University · USJohns Hopkins Medicine · USNational Kidney Foundation · USMedStar Heart & Vascular Institute · US

Funding

Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Determinants of chronic kidney disease in African-American live kidney donorsK01DK101677 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MASSIE, ALLAN B · 2015 to 2019
$789k
Aggressive Center Report Cards to Safely Increase Transplantation of Suboptimal KidneysK23DK115908 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GARONZIK WANG, JACQUELINE M · 2018 to 2021
$516k
Aggressive Organ Procurement Organization Report Cards to Safely Increase Kidney TransplantationF32DK124941 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BOYARSKY, BRIAN · 2020 to 2020
$81k
NIAID NIH HHS K24 AI144954NIDDK NIH HHS F32 DK124941NIDDK NIH HHS K01 DK101677NIDDK NIH HHS K23 DK115908
6 · The paper itself

Abstract

A widely accepted severe acute respiratory syndrome 2 (SARS-CoV-2) vaccine could protect vulnerable populations, but the willingness of solid organ transplant recipients (SOTRs) to accept a potential vaccine remains unknown.

methodsWe conducted a national survey of 1308 SOTRs and 1617 non-SOTRs between November 11 and December 2, 2020 through the network of the National Kidney Foundation.

resultsRespondents were largely White (73.2%), female (61.1%), and college graduates (56.2%). Among SOTRs, half (49.5%) were unsure or would be unwilling to receive a SARS-CoV-2 vaccine once available. Major concerns included potential side effects (85.2%), lack of rigor in the testing and development process (69.7%), and fear of incompatibility with organ transplants (75.4%). Even after the announcement of the high efficacy of the mRNA-1273 vaccine (Moderna Inc.) at the time of survey distribution, likeliness to receive a vaccine only slightly increased (53.5% before announcement versus 57.8% after the announcement). However, 86.8% of SOTRs would accept a vaccine if recommended by a transplant provider.

conclusionsSOTRs reported skepticism in receiving a potential SARS-CoV-2 vaccine, even after announcements of high vaccine efficacy. Reassuringly, transplant providers may be the defining influence in vaccine acceptance and will likely have a critical role to play in promoting vaccine adherence.

Identifiers

PMID34131585
PMCPMC8196090
OpenAlexW3171056757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.