Evidence map›Paper›PMID 34131555›Full record

ReviewApplied nanoscience2023

SARS-CoV-2 and its new variants: a comprehensive review on nanotechnological application insights into potential approaches.

Ramalingam Karthik Raja, Phuong Nguyen-Tri, Govindasamy Balasubramani, Arun Alagarsamy, Selcuk Hazir, Safa Ladhari, Alireza Saidi, Arivalagan Pugazhendhi, Arulandhu Anthoni Samy

Open access · bronzeAbstract readReview
In one paragraph

Review in Applied nanoscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Ramalingam Karthik RajaDepartment of Microbiology, Alagappa University, Karaikudi, Tamil Nadu 630003 India.ORCID 0000-0003-3782-046X
Phuong Nguyen-TriDepartment of Chemistry, Biochemistry and Physics, University du Québec àTrois-Rivieres, Trois-Rivieres, Canada.
Govindasamy BalasubramaniAquatic Animal Health and Environmental Division, ICAR-Central Institute of Brackishwater Aquaculture, Chennai, 600028 India.
Arun AlagarsamyDepartment of Microbiology, Alagappa University, Karaikudi, Tamil Nadu 630003 India.
Selcuk HazirDepartment of Biology, Faculty of Science and Arts, Adnan Menderes University, Aydin, Turkey.
Safa LadhariDepartment of Chemistry, Biochemistry and Physics, University du Québec àTrois-Rivieres, Trois-Rivieres, Canada.
Alireza SaidiInstitut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail (IRSST), 505 Boulevard de Maisonneuve O, Montréal, QC H3A 3C2 Canada.
Arivalagan PugazhendhiInnovative Green Product Synthesis and Renewable Environment Development Research Group, Faculty of Environment and Labour Safety, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Arulandhu Anthoni SamyCollege of Medical and Health Sciences, Wollega University, Nekemte, Ethiopia.
Alagappa University · INUniversité du Québec à Trois-Rivières · CAAdnan Menderes University · TRCentral Institute of Brackishwater Aquaculture · INInstitut de recherche Robert-Sauvé en santé et en sécurité du travail · CATon Duc Thang University · VNWollega University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 (COVID-19) spreads and develops quickly worldwide as a new global crisis which has left deep socio-economic damage and massive human mortality. This virus accounts for the ongoing outbreak and forces an urgent need to improve antiviral therapeutics and targeted diagnosing tools. Researchers have been working to find a new drug to combat the virus since the outbreak started in late 2019, but there are currently no successful drugs to control the SARS-CoV-2, which makes the situation riskier. Very recently, new variant of SARS-CoV-2 is identified in many countries which make the situation very critical. No successful treatment has yet been shown although enormous international commitment to combat this pandemic and the start of different clinical trials. Nanomedicine has outstanding potential to solve several specific health issues, like viruses, which are regarded a significant medical issue. In this review, we presented an up-to-date drug design strategy against SARS-CoV-2, including the development of novel drugs and repurposed product potentials were useful, and successful drugs discovery is a constant requirement. The use of nanomaterials in treatment against SARS-CoV-2 and their use as carriers for the transport of the most frequently used antiviral therapeutics are discussed systematically here. We also addressed the possibilities of practical applications of nanoparticles to give the status of COVID-19 antiviral systems.

Indexed as

AntiviralCoronavirusCOVID-19NanomaterialsSARS-CoV-2

Identifiers

PMID34131555
PMCPMC8190993
OpenAlexW3171604767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.