Evidence map›Paper›PMID 34131459›Full record

ArticlePaediatrics & child health2021

Efficacy and safety of paediatric medicinal cannabis use: A scoping review.

Colleen Pawliuk, Briana Chau, S Rod Rassekh, Terri McKellar, Harold Hal Siden

Open access · bronzeAbstract readScoping Review
In one paragraph

Article in Paediatrics & child health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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  10. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
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  11. Improving the regulation of medical cannabis in Canada to better serve pediatric patients.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Colleen PawliukDepartment of Paediatrics, BC Children's Hospital Research Institute, Vancouver, British Columbia.ORCID https://orcid.org/0000-0001-7507-8759
Briana ChauDepartment of Paediatrics, BC Children's Hospital Research Institute, Vancouver, British Columbia.
S Rod RassekhDepartment of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia.
Terri McKellarPhysiotherapy Association of British Columbia, Vancouver, British Columbia.
Harold Hal SidenDepartment of Paediatrics, BC Children's Hospital Research Institute, Vancouver, British Columbia.
BC Children's Hospital · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of medicinal cannabis in the paediatric age group is increasing despite the lack of evidence for its efficacy or safety.

objectiveTo map the available evidence on the efficacy and safety of medicinal cannabis in children and adolescents.

methodsWe conducted a scoping review and searched six electronic databases and grey literature. A study was eligible for inclusion when it investigated the efficacy or safety of medicinal cannabis for any condition, more than half of the participants were 0 to 18 years old, and had any study design except single case reports.

resultsWe included 36 studies in our final analysis, 32 of which investigated the efficacy or safety of cannabis in treatment-resistant epilepsy. The remaining 4 studies examined patients with cancer, dysautonomia, Epidermolysis Bullosa, and motor disorders.

conclusionsThere is a lack of evidence on the efficacy and safety of medicinal cannabis in most paediatric conditions.

Indexed as

CannabidiolCannabisDrug-resistant epilepsyMedicinal marijuanaScoping reviewTetrahydrocannabinoid

Identifiers

PMID34131459
PMCPMC8194766
OpenAlexW3022260478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.