Evidence map›Paper›PMID 34131452›Full record

ArticleProcedia computer science2021

Incorporating Time Delays in the Mathematical Modelling of the Human Immune Response in Viral Infections.

Gabrielle Dagasso, Joanna Urban, Mila Kwiatkowska

Open access · diamondAbstract read
In one paragraph

Article in Procedia computer science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gabrielle DagassoDepartment of Computing Science, Thompson Rivers University, Kamloops, 805 TRU Way, V2C 0C8, Canada.
Joanna UrbanDepartment of Biological Sciences, Thompson Rivers University, Kamloops, 805 TRU Way, V2C 0C8, Canada.
Mila KwiatkowskaDepartment of Computing Science, Thompson Rivers University, Kamloops, 805 TRU Way, V2C 0C8, Canada.
Thompson Rivers University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mathematical modelling helps to describe the functional and causal relationships between objects in the physical world. The complexity of these models increases as more components and variables are added to maintain and observe. Differential equations are regularly used in these models, as they are able to display the interactions between several variables and describe non-linear behaviour. Differential equations are commonly used in immune response mathematical models to help describe these complex and dynamic interactions within the immune system of the organism. Time delays in the immune system are common and are often disregarded due to the low-resolution of models, which provide limited description of the specific section of immune system being studied. The few models that incorporate time delays are mostly at the epidemiological level, to track the spread of the virus in the population. In this paper we review the applications of the models based on differential equations and describe their potential utilization for the studies of immune response in SARS-CoV-2.

Indexed as

Mathematical ModellingTime DelayViral Infection

Identifiers

PMID34131452
PMCPMC8191523
OpenAlexW3172923844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.