SynthesisEuropean journal of clinical nutrition2022
The effect of indirect calorimetry guided isocaloric nutrition on mortality in critically ill patients-a systematic review and meta-analysis.
Synthesis in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
- Indirect calorimetry-guided nutrition during weaning from prolonged mechanical ventilation: a double-blind randomized controlled trial.Critical care (London, England) · 2026Trial
- Article
- Effects of whole-body electromyostimulation as a time-efficient intervention on myokine profile and muscular performance in overweight adults: a randomized controlled study.Frontiers in sports and active living · 2026Article
- Phase-Related Resting Energy Expenditure in Critically Ill Adults: Metabolic Phenotypes and Determinants of Weight-Normalized Indices-A Retrospective Study.Journal of clinical medicine · 2025Article
- Novel Strategies to Promote Intensive Care Unit Recovery via Personalized Exercise, Nutrition, and Anabolic Interventions.Critical care clinics · 2025Review
- Nutritional Optimization of the Surgical Patient: A Narrative Review.Advances in nutrition (Bethesda, Md.) · 2025Review
- Personalized Nutrition in the Pediatric ICU: Steering the Shift from Acute Stress to Metabolic Recovery and Rehabilitation.Nutrients · 2024Review
- Nutrition in the intensive care unit: from the acute phase to beyond.Intensive care medicine · 2024Review
- Efficacy of permissive underfeeding for critically ill patients: an updated systematic review and trial sequential meta-analysis.Journal of intensive care · 2024Article
- Survey on Nutrition in Neurological Intensive Care Units (SONNIC)-A Cross-Sectional Survey among German-Speaking Neurointensivists on Medical Nutritional Therapy.Journal of clinical medicine · 2024Article
- [Laboratory and calorimetric monitoring of medical nutrition therapy in intensive and intermediate care units : Second position paper of the Section Metabolism and Nutrition of the German Interdisciplinary Association for Intensive Care and Emergency Medicine (DIVI)].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2023Review
- Personalized nutrition therapy in critical care: 10 expert recommendations.Critical care (London, England) · 2023Review
- Indirect Calorimetry in Spontaneously Breathing, Mechanically Ventilated and Extracorporeally Oxygenated Patients: An Engineering Review.Sensors (Basel, Switzerland) · 2023Review
- Association of nitrogen balance trajectories with clinical outcomes in critically ill COVID-19 patients: A retrospective cohort study.Clinical nutrition (Edinburgh, Scotland) · 2022Observational
- Article
- Clinical nutrition issues in 2022: What is missing to trust supplemental parenteral nutrition (SPN) in ICU patients?Critical care (London, England) · 2022Article
- Bioenergetic Balance of Continuous Venovenous Hemofiltration, a Retrospective Analysis.Nutrients · 2022Article
- Routine use of indirect calorimetry in critically ill patients: pros and cons.Critical care (London, England) · 2022Article
- PN Administration in Critically Ill Children in Different Phases of the Stress Response.Nutrients · 2022Review
- Effect of Whey Proteins on Malnutrition and Extubating Time of Critically Ill COVID-19 Patients.Nutrients · 2022Observational
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Indirect calorimetry (IC)-guided nutrition might positively affect the clinical outcome of critically ill patients. In this systematic review and meta-analysis, our objective was to assess the benefit of isocaloric nutrition guided by IC, compared to hypocaloric nutrition, for critically ill patients admitted to the intensive care unit (ICU). We performed a systematic review of all randomized controlled trials published through January 2021, assessing the benefit of isocaloric nutrition guided by IC. The primary outcome was 28-day all-cause mortality. Secondary outcomes were ICU and 90-day all-cause mortality, rate of nosocomial infections, and adverse events. Four trials evaluating 1052 patients were included. Patients treated with isocaloric nutrition had a lower 28-day mortality rate (risk ratio (RR) 0.79, 95% confidence interval (CI) 0.63-0.99, P = 0.04). No between-group difference was found in ICU and 90-day mortality (RR 0.92, 95% CI 0.68-1.23, P = 0.56 and RR 0.88, 95% CI 0.72-1.07; P = 0.2, respectively) and in the rate of nosocomial infections (RR 1.15, 95% CI 0.77-1.72, P = 0.51). A pooled analysis of studies that evaluated the benefit of isocaloric nutrition guided by IC, for critically ill patients in the ICU, has shown reduced 28-day mortality. However, there was no difference in 90-day mortality and nosocomial infection rate.
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