Evidence map›Paper›PMID 34131093›Full record

Trial reportAmerican journal of physical medicine & rehabilitation2021

Executive Function Moderates Functional Outcomes of Engagement Strategies During Rehabilitation in Older Adults.

Baris Ercal, Thomas L Rodebaugh, Marghuretta D Bland, Peggy Barco, Emily Lenard, Catherine E Lang, J Philip Miller, Michael Yingling, Eric J Lenze

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of physical medicine & rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Baris ErcalFrom the Healthy Mind Lab, Department of Psychiatry, Washington University School of Medicine in St. Louis (BE, EL, MY, EJL); Department of Psychological and Brain Sciences, Washington University in St. Louis (TLR); and Program in Physical Therapy (MDB, CEL), Program in Occupational Therapy (PB), and Division of Biostatistics (JPM), Washington University School of Medicine in St. Louis, Missouri.
Thomas L Rodebaugh
Marghuretta D Bland
Peggy Barco
Emily Lenard
Catherine E Lang
J Philip Miller
Michael Yingling
Eric J Lenze

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
ENHANCED MEDICAL REHABILITATION FOR OLDER ADULTSR01MH099011 · NIMH · WASHINGTON UNIVERSITY · PI LENZE, ERIC J · 2013 to 2017
$2.7M
Washington University Psychiatry Residency Research Education ProgramR25MH112473 · NIMH · WASHINGTON UNIVERSITY · PI NURI B FARBER, Timothy Eric Spiegel · 2018 to 2026
$1.6M
NCATS NIH HHS UL1 TR002345NIMH NIH HHS R01 MH099011NIMH NIH HHS R25 MH112473
6 · The paper itself

Abstract

objectiveThis study examined cognitive, affective, and medical impairments and their impact on rehabilitation approaches for improving functional outcome after hospitalization in older adults.

designA secondary analysis of a randomized clinical trial in 229 adults 65 yrs or older admitted to two skilled nursing facilities undergoing rehabilitation services was conducted. Patients were randomized to receive physical and occupational therapy by therapists trained in systematic approaches to engage patients, called Enhanced Medical Rehabilitation, or standard of care. The outcome of interest was functional improvement, defined as Barthel Index at discharge (controlling for Barthel Index upon admission). This study analyzed the relationship of measures of cognition, depression, and medical comorbidities as predictors of functional outcome and as moderators interacting with treatment group.

resultsClock drawing score moderated treatment effect size; the functional improvement of Enhanced Medical Rehabilitation over standard of care therapy reduced with increasing executive impairment. In contrast, general cognitive abilities, depression, medical comorbidities, and readiness for rehabilitation were neither predictors nor moderators of functional improvement.

conclusionsFor older adults undergoing rehabilitation, greater functional improvement with the motivational techniques of Enhanced Medical Rehabilitation was contingent on patients having intact executive function. Given that executive function impairments are common in rehabilitation populations, new strategies are needed to improve treatment outcomes in physical/occupational therapy. TO CLAIM CME CREDITS: Complete the self-assessment activity and evaluation online at http://www.physiatry.org/JournalCME. CME

objectivesUpon completion of this article, the reader should be able to (1) Discuss the role of baseline affective, cognitive, and medical impairments in impacting functional outcomes of older adults undergoing rehabilitation; (2) Describe the behavioral change and motivational approaches that are core features of the novel intervention known as Enhanced Medical Rehabilitation (E-MR); and (3) Determine the role of baseline executive function in moderating the effect of rehabilitation intervention on functional outcomes in older adults. LEVEL: Advanced. ACCREDITATION: The Association of Academic Physiatrists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.The Association of Academic Physiatrists designates this Journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Indexed as

Occupational TherapyPhysical Therapy ModalitiesAgedAged, 80 and overExecutive FunctionFemaleHumansMalePersons with DisabilitiesRecovery of FunctionSkilled Nursing Facilities

Identifiers

PMID34131093
PMCPMC8260037

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.