Evidence map›Paper›PMID 34131082›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

An RNA-centric global view of

Manuela Fuchs, Vanessa Lamm-Schmidt, Johannes Sulzer, Falk Ponath, Laura Jenniches, Joseph A Kirk, Robert P Fagan, Lars Barquist, Jörg Vogel, Franziska Faber

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 63 citations in OpenAlex.

  1. Defining the order of assembly of theJournal of bacteriology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. RNAP-seq:bioRxiv : the preprint server for biology · 2026
    Article
  6. CenIR, an essential BlaIR-family regulatory system inbioRxiv : the preprint server for biology · 2026
    Article
  7. A set of genetic tools for use inMicrobiology (Reading, England) · 2026
    Article
  8. Defining the order of assembly of thebioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. The current riboswitch landscape inMicrobiology (Reading, England) · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Manuela FuchsInstitute for Molecular Infection Biology, Faculty of Medicine, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-7804-1959
Vanessa Lamm-SchmidtInstitute for Molecular Infection Biology, Faculty of Medicine, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0003-4281-8006
Johannes SulzerInstitute for Molecular Infection Biology, Faculty of Medicine, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-2800-9328
Falk PonathHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, 97080 Würzburg, Germany.ORCID 0000-0002-2144-0545
Laura JennichesHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, 97080 Würzburg, Germany.
Joseph A KirkThe Florey Institute, Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom.
Robert P FaganThe Florey Institute, Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom.ORCID 0000-0002-8704-4828
Lars BarquistHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, 97080 Würzburg, Germany.
Jörg VogelInstitute for Molecular Infection Biology, Faculty of Medicine, University of Würzburg, 97080 Würzburg, Germany.
Franziska FaberInstitute for Molecular Infection Biology, Faculty of Medicine, University of Würzburg, 97080 Würzburg, Germany; franziska.faber@uni-wuerzburg.de.ORCID 0000-0002-8700-6522
University of Würzburg · DEHelmholtz Centre for Infection Research · DEUniversity of Sheffield · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

The gram-positive human pathogen

Indexed as

5' Untranslated RegionsClostridioides difficileEnvironmentEthanolamineGenome, BacterialHost Factor 1 ProteinLigandsMolecular ChaperonesMolecular Sequence AnnotationOpen Reading FramesOperonPromoter Regions, GeneticRNA, BacterialRNA, UntranslatedTranscription Initiation SiteTranscription Termination, Genetic5' Untranslated RegionsEthanolamineHost Factor 1 ProteinLigandsMolecular ChaperonesRNA, BacterialRNA, UntranslatedC. difficiledifferential RNA-seqHfqsmall RNAtranscript termination site

Identifiers

PMID34131082
PMCPMC8237595
OpenAlexW3167448284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.