Evidence map›Paper›PMID 34130904›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2021

Two Pathways to Self-Harm in Adolescence.

Stepheni Uh, Edwin S Dalmaijer, Roma Siugzdaite, Tamsin J Ford, Duncan E Astle

Abstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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  10. Predicting the trajectory of non-suicidal self-injury among adolescents.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Article
  11. Article
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  15. Predictors of teen sexual behavior.Children and youth services review · 2024
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  20. Statistical power for cluster analysis.BMC bioinformatics · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Stepheni UhMs. Uh and Drs. Dalmaijer, Siugzdaite, and Astle are with MRC Cognition and Brain Sciences Unit, University of Cambridge, United Kingdom. Electronic address: stepheni.uh@mrc-cbu.cam.ac.uk.
Edwin S DalmaijerMs. Uh and Drs. Dalmaijer, Siugzdaite, and Astle are with MRC Cognition and Brain Sciences Unit, University of Cambridge, United Kingdom.
Roma SiugzdaiteMs. Uh and Drs. Dalmaijer, Siugzdaite, and Astle are with MRC Cognition and Brain Sciences Unit, University of Cambridge, United Kingdom.
Tamsin J FordDr. Ford is with the University of Cambridge, United Kingdom.
Duncan E AstleMs. Uh and Drs. Dalmaijer, Siugzdaite, and Astle are with MRC Cognition and Brain Sciences Unit, University of Cambridge, United Kingdom.

Funding

Medical Research Council G108/625Medical Research Council MC-A0606-5PQ41Medical Research Council MC_UU_00005/2
6 · The paper itself

Abstract

objectiveThe behavioral and emotional profiles underlying adolescent self-harm, and its developmental risk factors, are relatively unknown. We aimed to identify subgroups of young people who self-harm (YPSH) and longitudinal risk factors leading to self-harm.

methodParticipants were from the Millennium Cohort Study (N = 10,827). A clustering algorithm was used to identify subgroups who self-harmed with different behavioral and emotional profiles at age 14 years. We then traced the profiles back in time (ages 5-14 years) and used feature selection analyses to identify concurrent correlates and longitudinal risk factors of self-harming behavior.

resultsThere were 2 distinct subgroups at age 14 years: a smaller group (n = 379) who reported a long history of psychopathology, and a second, much larger group (n = 905) without. Notably, both groups could be predicted almost a decade before the reported self-harm. They were similarly characterized by sleep problems and low self-esteem, but there was developmental differentiation. From an early age, the first group had poorer emotion regulation, were bullied, and their caregivers faced emotional challenges. The second group showed less consistency in early childhood, but later reported more willingness to take risks and less security with peers/family.

conclusionOur results uncover 2 distinct pathways to self-harm: a "psychopathology" pathway, associated with early and persistent emotional difficulties and bullying; and an "adolescent risky behavior" pathway, whereby risk taking and external challenges emerge later into adolescence and are associated with self-harm. At least one of these pathways has a long developmental history, providing an extended window for interventions as well as potential improvements in the identification of children at risk, biopsychosocial causes, and treatment or prevention of self-harm.

Indexed as

Adolescent BehaviorBullyingSelf-Injurious BehaviorAdolescentChildChild, PreschoolCohort StudiesHumansPeer GroupRisk Factorsadolescencelongitudinal analysisself-harmsocioemotional profiles

Identifiers

PMID34130904
PMCPMC8661039

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.