Evidence map›Paper›PMID 34130782›Full record

SynthesisZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2021

[Efficacy of probiotics in preventing late-onset sepsis in very low birth weight infants: a Meta analysis].

Jie-Yong Li, Zhi-Xun He, Wei-Ming Wang, Cai Lin

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jie-Yong LiDepartment of Neonatology, First People's Hospital of Zhaoqing, Zhaoqing, Guangdong 526000, China.
Zhi-Xun HeDepartment of Neonatology, First People's Hospital of Zhaoqing, Zhaoqing, Guangdong 526000, China.
Wei-Ming WangDepartment of Neonatology, First People's Hospital of Zhaoqing, Zhaoqing, Guangdong 526000, China.
Cai LinDepartment of Neonatology, First People's Hospital of Zhaoqing, Zhaoqing, Guangdong 526000, China.
The First People's Hospital of Zhaoqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the efficacy of probiotics in preventing late-onset sepsis (LOS) in very low birth weight (VLBW) infants.

methodsDatabases including PubMed, Web of Science, Cochrane Library, Wanfang Data, China National Knowledge Infrastructure, and Chinese Biomedical Literature Database were searched for randomized controlled trials (RCTs) of probiotics in preventing LOS in VLBW infants. LOS was classified as clinical LOS and confirmed LOS. RevMan 5.4 was used to perform the Meta analysis.

resultsA total of 31 RCTs were included, with 3 490 VLBW infants in the probiotics group and 3 376 VLBW infants in the control group. The Meta analysis showed that compared with the control group, the probiotics group had significantly lower risks of clinical LOS (

conclusionsCurrent evidence indicates that probiotics may reduce the risk of clinical LOS and clinical/confirmed LOS in VLBW infants, and the risk of confirmed LOS in VLBW infants who are exclusively breastfed.

Indexed as

ProbioticsSepsisChinaFemaleHumansInfantInfant, NewbornInfant, PrematureInfant, Very Low Birth Weight

Identifiers

PMID34130782
PMCPMC8214000
OpenAlexW3168163800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.