ArticleJournal of foot and ankle research2021
Duration of total contact casting for resolution of acute Charcot foot: a retrospective cohort study.
Article in Journal of foot and ankle research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- To Assess the Variation in the Definitions Used to Describe the Stages of Acute Charcot Neuro-Osteoarthropathy (Diagnosis, Remission and Relapse): A Systematic Review.Journal of foot and ankle research · 2025Pooled it
- Plantar Pressure and Radiographic Deformity at Diagnosis of Active Charcot Neuro-Osteoarthropathy as Potential Prognostic Markers for Time to Remission.Journal of clinical medicine · 2026Article
- Long-term limb salvage and functional recovery in advanced Charcot neuroarthropathy complicated by a non-healing diabetic foot ulcer: a CARE-compliant case report.Frontiers in endocrinology · 2026Article
- [Diabetic Charcot neuroarthropathy initially misdiagnosed as rheumatoid arthritis and gout: A case report].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Article
- Improving Diabetic Foot Care Through a Multidisciplinary Clinic: Experience From Pilgrim Hospital, UK.Cureus · 2025Article
- Charcot foot disease: A new approach.Drugs & aging · 2025Review
- Optimal Time Period to Achieve Temperature Stabilisation After Total Contact Cast (TCC) Removal for Assessing Dermal Temperatures in Active Charcot Neuro-Osteoarthropathy.Journal of foot and ankle research · 2025Article
- Demographic and Clinical Characteristics of Patients With Charcot Neuro-Osteoarthropathy in People With Diabetes Mellitus in Six Countries: A Multicenter Observational Study From 1996 to 2022.Journal of diabetes research · 2025Observational
- Early Treatment of Acute Stage 0/1 Diabetic Charcot Foot Can Avoid Major Amputations at One Year.Journal of clinical medicine · 2024Article
- Weight bearing versus non-weight bearing total contact cast in the management of active Charcot foot: A systematic review.SAGE open medicine · 2024Review
- [Progress in clinical diagnosis and treatment of diabetic Charcot neuroarthropathy of foot and ankle].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023Article
- Orthotic approach to prevention and management of diabetic foot: A narrative review.World journal of diabetes · 2022Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCharcot neuroarthropathy (Charcot foot) is a highly destructive joint disease of the foot and ankle. If there is delayed diagnosis and treatment, it can lead to gross deformity, instability, recurrent ulceration and/or amputation. Total contact casting (TCC) is a treatment commonly used to immobilise the foot and ankle to prevent trauma, further destruction and preserve the foot structure during the inflammatory phase. At present, there is limited Australian data regarding the duration of TCC treatment for resolution of acute Charcot foot, and whether there are any patient and clinical factors affecting its duration. Therefore, this study aimed to address these deficiencies.
methodsThis study presents a retrospective analysis of 27 patients with acute Charcot foot attending for TCC treatment at a high-risk foot service (HRFS) in a large metropolitan health network in Melbourne, Australia. Over a three-year period, data were retrospectively collected by reviewing hospital medical records for clinical, demographic, medical imaging and foot examination information. To explore between-group differences, independent samples t-tests, Mann-Whitney U tests, Chi-square tests, and/or Fisher's exact tests were calculated depending on data type. To evaluate associations between recorded variables and duration of TCC treatment, mean differences, odds ratios (OR) and 95% confidence intervals were calculated.
resultsMean age was 57.9 (SD, 12.6) years, 66.7% were male, 88.9% had diabetes, 96.3% had peripheral neuropathy, and 33.3% had peripheral arterial disease. Charcot misdiagnosis occurred in 63.0% of participants, and signs and symptoms consistent with acute Charcot foot were present for a median of 2.0 (IQR, 1.0 to 6.0) months prior to presenting or being referred to the HRFS. All participants had stage 1 Charcot foot. Of these, the majority were located in the tarsometatarsal joints (44.4%) or midfoot (40.7%) and were triggered by an ulcer or traumatic injury (85.2%). The median TCC duration for resolution of acute Charcot foot was 4.3 (IQR, 2.7 to 7.8) months, with an overall complication rate of 5% per cast. Skin rubbing/irritation (40.7%) and asymmetry pain (22.2%) were the most common TCC complications. Osteoarthritis was significantly associated with a TCC duration of more than 4 months (OR, 6.00). Post TCC treatment, 48.1% returned to footwear with custom foot orthoses, 25.9% used a life-long Charcot Restraint Orthotic Walker, and 22.2% had soft tissue or bone reconstructive surgery. There were no Charcot recurrences, however, contralateral Charcot occurred in 3 (11.1%) participants.
conclusionsThe median TCC duration for resolution of acute Charcot foot was 4 months, which is shorter or comparable to data reported in the United Kingdom, United States, Europe, and other Asia Pacific countries. Osteoarthritis was significantly associated with a longer TCC duration. The findings from this study may assist clinicians in providing patient education, managing expectations and improving adherence to TCC treatment for acute Charcot neuroarthropathy cases in Australia.
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