ArticleProceedings of the National Academy of Sciences of the United States of America1988
Cleavage furrow isolated from newt eggs: contraction, organization of the actin filaments, and protein components of the furrow.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 86 citations in OpenAlex.
- Hubbing the Cancer Cell.Cancers · 2022Review
- Filament-guided filament assembly provides structural memory of filament alignment during cytokinesis.Developmental cell · 2021Article
- Review
- Animal Cell Cytokinesis: The Rho-Dependent Actomyosin-Anilloseptin Contractile Ring as a Membrane Microdomain Gathering, Compressing, and Sorting Machine.Frontiers in cell and developmental biology · 2020Article
- Equatorial Non-muscle Myosin II and Plastin Cooperate to Align and Compact F-actin Bundles in the Cytokinetic Ring.Frontiers in cell and developmental biology · 2020Article
- Molecular form and function of the cytokinetic ring.Journal of cell science · 2019Review
- Structure of the fission yeast actomyosin ring during constriction.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Cytokinesis in Metazoa and Fungi.Cold Spring Harbor perspectives in biology · 2017Review
- The ultrastructural organization of actin and myosin II filaments in the contractile ring: new support for an old model of cytokinesis.Molecular biology of the cell · 2017Article
- Vertebrate Embryonic Cleavage Pattern Determination.Advances in experimental medicine and biology · 2017Review
- Robust gap repair in the contractile ring ensures timely completion of cytokinesis.The Journal of cell biology · 2016Article
- Still and rotating myosin clusters determine cytokinetic ring constriction.Nature communications · 2016Article
- In vitro contraction of cytokinetic ring depends on myosin II but not on actin dynamics.Nature cell biology · 2013Article
- Actin depolymerization drives actomyosin ring contraction during budding yeast cytokinesis.Developmental cell · 2012Article
- Rho-associated kinase-dependent contraction of stress fibres and the organization of focal adhesions.Journal of the Royal Society, Interface · 2011Review
- Isolation and partial purification of the Saccharomyces cerevisiae cytokinetic apparatus.Cytoskeleton (Hoboken, N.J.) · 2010Article
- Fission yeast IQGAP arranges actin filaments into the cytokinetic contractile ring.The EMBO journal · 2009Article
- mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells.Molecular biology of the cell · 2008Article
- Calcium signalling during the cleavage period of zebrafish development.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2008Review
- Role of stress fibers and focal adhesions as a mediator for mechano-signal transduction in endothelial cells in situ.Vascular health and risk management · 2008Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cleavage-furrow region was isolated surgically from newt eggs at the early stage of the first cleavage. The isolated furrow contracted in the presence of ATP at a Ca2+ concentration of 10 or 100 nM, although the speed was less than that of the furrow in vivo. Cytochalasin B, cytochalasin D, phalloidin, p-chloromercuribenzoate, and N-ethyl-maleimide interfered with the contraction, but colchicine did not. The furrow contained bundles of actin filaments of opposite polarities oriented parallel to the long axis of the furrow; these bundles may be the main component of the contractile arc. From electron microscopic observation of thin sections of the furrow, it was suggested that the actin bundles of the contractile arc were organized from preexisting cortical filaments that were connected to the plasma membrane by granular materials at their barbed ends. Contractile-arc actin filaments were revealed to be crosslinked by thin strands by the rapid freezing/deep etching-replication technique. Two-dimensional polyacrylamide gel electrophoresis showed that several proteins found in the furrow cortex are absent from the cortical layer before the cleavage furrow is formed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.