Evidence map›Paper›PMID 34130662›Full record

ArticleBMC infectious diseases2021

Adenosine deaminase negative pleural tuberculosis: a case report.

Zachary H Boggs, Scott Heysell, Joshua Eby, Christopher Arnold

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zachary H BoggsUniversity of Virginia, Charlottesville, VA, 22903, USA. zb3ca@virginia.edu.ORCID http://orcid.org/0000-0002-3551-3901
Scott HeysellUniversity of Virginia, Charlottesville, VA, 22903, USA.
Joshua EbyUniversity of Virginia, Charlottesville, VA, 22903, USA.
Christopher ArnoldUniversity of Virginia, Charlottesville, VA, 22903, USA.
University of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA pleural fluid adenosine deaminase (ADA) has been used globally to assist in the diagnosis of a tuberculous pleural effusion (TPE) with a notable negative predictive value. CASE PRESENTATION: We report a case of a patient with a negative pleural fluid ADA who was found to have culture-positive and biopsy-proven Mycobacterium tuberculosis.

conclusionsThis case shows the importance of pursuing gold standard diagnostic studies when clinical suspicion remains high despite negative preliminary testing. We further describe gaps in research to improve pleural fluid biomarkers for TPE.

Indexed as

Adenosine DeaminaseAdultAntitubercular AgentsBiomarkersBiopsyExudates and TransudatesHumansMaleMycobacterium tuberculosisPleural EffusionPredictive Value of TestsTreatment OutcomeTuberculosis, PleuralAdenosine DeaminaseAntitubercular AgentsBiomarkersAdenosine deaminaseCase reportIGRAPleural effusionTuberculosis

Identifiers

PMID34130662
PMCPMC8204465
OpenAlexW3172718784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.