Evidence map›Paper›PMID 34130635›Full record

ArticleBMC infectious diseases2021

Case report: first symptomatic Candidatus Neoehrlichia mikurensis infection in Slovenia.

Mitja Lenart, Miha Simoniti, Katja Strašek-Smrdel, Vesna Cvitković Špik, Tanja Selič-Kurinčič, Tatjana Avšič-Županc

Abstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Molecular detection and characterization ofInternational journal for parasitology. Parasites and wildlife · 2025
    Article
  2. Article
  3. Review
  4. Detection and phylogenetic classification ofFrontiers in microbiology · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mitja LenartDepartment of Infectious diseases, General Hospital Celje, Oblakova ulica 5, 3000, Celje, Slovenia. mitchu88@gmail.com.ORCID http://orcid.org/0000-0003-3657-0999
Miha SimonitiDepartment of Infectious diseases, General Hospital Celje, Oblakova ulica 5, 3000, Celje, Slovenia.
Katja Strašek-SmrdelFaculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana, Zaloška cesta 4, Ljubljana, 1000, Slovenia.
Vesna Cvitković ŠpikFaculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana, Zaloška cesta 4, Ljubljana, 1000, Slovenia.
Tanja Selič-KurinčičDepartment of Infectious diseases, General Hospital Celje, Oblakova ulica 5, 3000, Celje, Slovenia.
Tatjana Avšič-ŽupancFaculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana, Zaloška cesta 4, Ljubljana, 1000, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCandidatus Neoehrlichia mikurensis (CNM) is an emerging tick-born pathogen and usually causes symptomatic infection only in immunocompromised patients. Apart from one described case found in the literature where cultivation was successful, all cases so far were diagnosed by using broad-range 16S rDNA PCR. CASE PRESENTATION: Our patient presented with a prolonged febrile state of unknown origin. Clinical presentation, extensive medical workup and classic microbiologic testing were non-conclusive. Several infectious agents and other causes for the febrile state were excluded. In the end, a broad-range 16S rDNA PCR was to be performed to confirm the diagnosis of CNM infection. Treatment was successful with doxycycline.

conclusionsDue to the obscurity of the pathogen, diagnostic workup in CNM is prolonged and challenging. More awareness is need about this emerging infectious disease in countries with high prevalence of tick-borne diseases as standard microbiological methods are not successful in confirming the diagnosis.

Indexed as

AgedAnaplasmataceaeAnaplasmataceae InfectionsAnimalsAnti-Bacterial AgentsCommunicable Diseases, EmergingDoxycyclineFemaleHumansIxodesPolymerase Chain ReactionPrevalenceRNA, Ribosomal, 16SSloveniaTick-Borne DiseasesTicksAnti-Bacterial AgentsDoxycyclineRNA, Ribosomal, 16S16S rRNA PCRCandidatus Neoehrlichia mikurensisFever of unknown originImmunocompromisedInfectionTick

Identifiers

PMID34130635
PMCPMC8207769

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.