Evidence map›Paper›PMID 34130514›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2021

Bioelectric, tissue, and molecular characteristics of the gastric mucosa at different times of ischemia.

Peña-Mercado Eduardo, Garcia-Lorenzana Mario, Patiño-Morales Carlos César, Montecillo-Aguado Mayra, Huerta-Yepez Sara, Beltran Nohra E

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In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Peña-Mercado EduardoPosgrado en Ciencias Naturales e Ingenieria, Unidad Cuajimalpa, Universidad Autonoma Metropolitana, CDMX 05340, Mexico.ORCID 0000-0001-7942-9624
Garcia-Lorenzana MarioDepartamento de Biologia de la Reproduccion, Unidad Iztapalapa, Universidad Autonoma Metropolitana, CDMX 09340, Mexico.
Patiño-Morales Carlos CésarLaboratorio de Investigacion en Biologia del Desarrollo y Teratogenesis Experimental, Hospital Infantil de Mexico, Federico Gomez, CDMX 06720, Mexico.
Montecillo-Aguado MayraDoctorado en Ciencias Biologicas, Facultad de Medicina, Universidad Nacional Autonoma de Mexico, CDMX 04510, Mexico.
Huerta-Yepez SaraUnidad de Investigacion en Enfermedades Hematoncologicas, Hospital Infantil de Mexico, Federico Gomez, CDMX 06720, Mexico.
Beltran Nohra EDepartamento de Procesos y Tecnologia, Unidad Cuajimalpa, Universidad Autonoma Metropolitana, CDMX 05340, Mexico.ORCID 0000-0001-7490-9127
Universidad Autónoma Metropolitana · MXHospital Infantil de México Federico Gómez · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal ischemia may be presented as a complication associated with late shock detection in patients in critical condition. Prolonged ischemia can cause mucosal integrity to lose its barrier function, triggering alterations that can induce organ dysfunction and lead to death. Electrical impedance spectroscopy has been proposed to identify early alteration in ischemia-induced gastric mucosa in this type of patients. This work analyzed changes in impedance parameters, and tissue and molecular alterations that allow us to identify the time of ischemia in which the gastric mucosa still maintains its barrier function. The animals were randomly distributed in four groups: Control, Ischemia 60, 90, and 120 min. Impedance parameters were measured and predictive values were determined to categorize the degree of injury using a receiver operating characteristic curve. Markers of inflammatory process and apoptosis (iNOS, TNFα, COX-2, and Caspase-3) were analyzed. The largest increase in impedance parameters occurred in the ischemia 90 and 120 min groups, with resistance at low frequencies (R

Indexed as

AnimalsCyclooxygenase 2Electric ImpedanceGastric MucosaIschemiaMaleRatsRats, WistarReperfusion InjuryTime FactorsCyclooxygenase 2bioimpedancebiomarkersdigital pathologyelectrical impedance spectroscopygastric impedance parametersGastric ischemia

Identifiers

PMID34130514
PMCPMC8474982
OpenAlexW3170294924

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.