Evidence map›Paper›PMID 34130442›Full record

ArticlePsychiatry investigation2021

Do Anxiety and Depression Levels Affect the Inflammation Response in Patients Hospitalized for COVID-19.

Aybeniz Civan Kahve, Hasan Kaya, Merve Okuyucu, Erol Goka, Sureyya Barun, Yunus Hacimusalar

Open access · diamondAbstract read
In one paragraph

Article in Psychiatry investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Aybeniz Civan KahveDepartment of Psychiatry, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Hasan KayaDepartment of Psychiatry, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Merve OkuyucuDepartment of Child and Adolescent Psychiatry, Yildirim Beyazit University Faculty of Medicine, Ankara, Turkey.
Erol GokaDepartment of Psychiatry, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Sureyya BarunDepartment of Medical Pharmacology, Gazi University Faculty of Medicine, Ankara, Turkey.
Yunus HacimusalarDepartment of Psychiatry, University of Health Sciences, Kayseri City Hospital, Kayseri, Turkey.
Sağlık Bilimleri Üniversitesi · TRAnkara Yıldırım Beyazıt University · TRGazi University · TRKayseri Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe whole world is still struggling with the COVID-19 pandemic. Inflammation response, thought to be associated with severe illness and death, is an important research topic in COVID-19. Inflammation is also an essential condition explored in psychiatric illnesses. Our knowledge about the relationship between the inflammation response and psychiatric comorbidities in patients with COVID-19 is very limited. In this study, the relationship between anxiety and depression levels and inflammation response of patients with COVID-19 hospitalized in the hospital was examined.

methods175 patients were included in the study. Sociodemographic Data Form, Beck Depression Inventory and Beck Anxiety Inventory were applied to the patients. To evaluate the inflammation responses, blood sedimentation rate, C-reactive protein (CRP), procalcitonin, ferritin, neutrophil/lymphocyte ratio (NLR), and IL-6 levels were examined.

resultsIn our study, no relationship was found between anxiety and depression levels and inflammatory responses in patients hospitalized with a diagnosis of COVID-19. Anxiety and depression levels of women were higher than men, and NLR, ferritin, IL-6 levels were found to be lower than men. Anxiety levels increase with age. There is a positive correlation between NLR and ferritin levels and duration of hospitalization.

conclusionOur study examining the relationship of psychiatric comorbidities with the inflammation response and our increasing literature knowledge, together with studies evaluating the mental effects of COVID-19, suggest that determining the relationship between inflammation responses and psychiatric comorbidities in COVID-19, whose pathophysiology has not been clarified yet, maybe an essential step in interventions on the course of the disease.

Indexed as

AnxietyCOVID-19DepressionInflammationPlasma biomarkers

Identifiers

PMID34130442
PMCPMC8256149
OpenAlexW3170491452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.