Evidence map›Paper›PMID 34129605›Full record

ArticlePloS one2021

Age-preserved semantic memory and the CRUNCH effect manifested as differential semantic control networks: An fMRI study.

Niobe Haitas, Mahnoush Amiri, Maximiliano Wilson, Yves Joanette, Jason Steffener

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Post-COVID-19 conditions: a systematic review on advanced magnetic resonance neuroimaging findings.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
  2. Article
  3. Article
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  5. Mnemonic But Not Contextual Feedback Signals Defy Dedifferentiation in the Aging Early Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Niobe HaitasLaboratory of Communication and Aging, Institut Universitaire de Gériatrie de Montréal, Montreal, Quebec, Canada.ORCID 0000-0003-4221-8940
Mahnoush AmiriLaboratory of Communication and Aging, Institut Universitaire de Gériatrie de Montréal, Montreal, Quebec, Canada.
Maximiliano WilsonCentre de Recherche CERVO - CIUSSS de la Capitale-Nationale et Département de Réadaptation, Université Laval, Quebec City, Quebec, Canada.
Yves JoanetteLaboratory of Communication and Aging, Institut Universitaire de Gériatrie de Montréal, Montreal, Quebec, Canada.
Jason SteffenerInterdisciplinary School of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.
Institut Universitaire de Gériatrie de Montréal · CACentre for Interdisciplinary Research in Rehabilitation · CAUniversity of Ottawa · CA

Funding

CIHR
6 · The paper itself

Abstract

Semantic memory representations are overall well-maintained in aging whereas semantic control is thought to be more affected. To explain this phenomenon, this study aims to test the predictions of the Compensation Related Utilization of Neural Circuits Hypothesis (CRUNCH) focusing on task demands in aging as a possible framework. The CRUNCH effect would manifest itself in semantic tasks through a compensatory increase in neural activation in semantic control network regions but only up to a certain threshold of task demands. This study will compare 40 young (20-35 years old) with 40 older participants (60-75 years old) in a triad-based semantic judgment task performed in an fMRI scanner while manipulating levels of task demands (low vs. high) through semantic distance. In line with the CRUNCH predictions, differences in neurofunctional activation and behavioral performance (accuracy and response times) are expected in young vs. old participants in the low- vs. high-demand conditions manifested in semantic control Regions of Interest.

Indexed as

AdultAgedAge FactorsBrainBrain MappingFemaleHumansMagnetic Resonance ImagingMaleMemoryMemory DisordersMiddle AgedPsychomotor PerformanceReaction TimeSemantics

Identifiers

PMID34129605
PMCPMC8205163
OpenAlexW3166156277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.