Evidence map›Paper›PMID 34129098›Full record

ReviewArchives of dermatological research2022

Chronic itch in African Americans: an unmet need.

Giuseppe Ingrasci, Nour El-Kashlan, Andrew Alexis, Gil Yosipovitch

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of dermatological research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Host-Microbiome Interactions in Chronic Itch.Journal of clinical medicine · 2025
    Review
  5. Review
  6. Association of Liver Disease and Chronic Pruritus: A Case-Control Study.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  7. Scars.Nature reviews. Disease primers · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Giuseppe IngrasciDr. Phillip Frost Department of Dermatology and Miami Itch Center, University of Miami, Miami, FL, USA.
Nour El-KashlanThe Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Andrew AlexisThe Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gil YosipovitchDr. Phillip Frost Department of Dermatology and Miami Itch Center, University of Miami, Miami, FL, USA. gyosipovitch@med.miami.edu.
Icahn School of Medicine at Mount Sinai · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pruritus carries a significant burden of disease and is associated with a negative impact on quality of life. African Americans are disproportionately burdened by chronic pruritic disorders, including but not limited to atopic dermatitis, prurigo nodularis, inflammatory scalp dermatoses, pathologic scarring, and HIV-related dermatoses. Racial differences in skin structure and function may contribute to the pathogenesis of itch in African Americans. Itch perception and response to treatment in African Americans remain understudied and not well understood. As such, there is a large unmet need with regard to the knowledge and management of pruritus in African Americans. This review highlights notable differences in the epidemiology, pathophysiology, genetic predisposition, clinical presentation, and response to treatment for select pruritic skin conditions. By addressing itch as an unmet need in African Americans, we hope to improve patient outcomes and lessen disparities in dermatologic care.

Indexed as

Black or African AmericanDermatitis, AtopicChronic DiseaseHumansPruritusQuality of LifeAcne keloidalis nuchaeAfrican AmericansAtopic dermatitisCentral centrifugal cicatricial alopeciaChronic itchHypertrophic scar formationKeloidPost-burn pruritusPrurigo nodularisPruritic papular eruption of HIVPruritusSeborrheic dermatitis

Identifiers

PMID34129098
OpenAlexW3166644150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.