Evidence map›Paper›PMID 34128694›Full record

ArticlemSystems2021

Longxian Lv, Chunyan Yao, Ren Yan, Huiyong Jiang, Qiangqiang Wang, Kaicen Wang, Siqi Ren, Shandong Jiang, Jiafeng Xia, Shengjie Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Effects ofGut microbes · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Bioactive Metabolites fromCurrent developments in nutrition · 2026
    Article
  7. The Gut Microbiota in Elderly Patients with Acute Hepatitis E Infection.Journal of clinical and translational hepatology · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Extract ofAntioxidants (Basel, Switzerland) · 2024
    Article
  13. Review
  14. Article
  15. Nutrients · 2023
    Article
  16. Article
  17. Article
  18. Probiotics-FermentedInternational journal of molecular sciences · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Longxian Lv *State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang Universitygrid.13402.34, Hangzhou, China.
Chunyan Yao *Key Laboratory of Nutrition of Zhejiang Province, Institute of Health Food, Hangzhou Medical College, Hangzhou, China.
Ren Yan *State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang Universitygrid.13402.34, Hangzhou, China.
Huiyong Jiang *State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang Universitygrid.13402.34, Hangzhou, China.
Qiangqiang WangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang Universitygrid.13402.34, Hangzhou, China.
Kaicen WangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang Universitygrid.13402.34, Hangzhou, China.
Siqi RenSchool of Pharmacy, Hangzhou Medical College, Hangzhou, China.
Shandong JiangDepartment of Clinical Medicine, Hangzhou Medical College, Hangzhou, China.
Jiafeng XiaState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang Universitygrid.13402.34, Hangzhou, China.
Shengjie LiState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang Universitygrid.13402.34, Hangzhou, China.
Ying YuKey Laboratory of Nutrition of Zhejiang Province, Institute of Health Food, Hangzhou Medical College, Hangzhou, China.
State Key Laboratory of Diagnosis and Treatment of Infectious DiseasesHangzhou Medical College · CN

Funding

Key Subjects of Nutrition of Zhejiang Province 11-zc03MOST | National Key Research and Development Program of China (973 Program) 2018YFC2000500National Natural Science Foundation of China (NSFC) 81570512National Natural Science Foundation of China (NSFC) 81790631National Natural Science Foundation of China (NSFC) 81790634Natural Science Foundation of Zhejiang Province () LQ19H030007Natural Science Foundation of Zhejiang Province () LQY18H280001Zhejiang Provincial Science and Technology Department 1924D
6 · The paper itself

Abstract

Although the probiotic Lactobacillus acidophilus LA14 is used worldwide, its effect on liver diseases remains unelucidated. Here, 32 rats were divided into four groups, gavaged with L. acidophilus LA14 (3 × 10

Indexed as

acute liver injuryLactobacillus acidophilusmetabolomemicrobiotatranscriptome

Identifiers

PMID34128694
PMCPMC8269229
OpenAlexW3166279084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.