Evidence map›Paper›PMID 34128512›Full record

ReviewChemical Society reviews2021

Hydroxyl radical is a significant player in oxidative DNA damage in vivo.

Barry Halliwell, Amitava Adhikary, Michael Dingfelder, Miral Dizdaroglu

Open access · greenAbstract readReview
In one paragraph

Review in Chemical Society reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
28.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 295 citations in OpenAlex.

  1. Review
  2. Article
  3. Theoretical studies to understand theJournal of molecular modeling · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Urate as a COAntioxidants (Basel, Switzerland) · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Barry HalliwellDepartment of Biochemistry, National University of Singapore, Centre for Life Sciences, #05-01A, 28 Medical Drive, 117456, Singapore. bchbh@nus.edu.sg.
Amitava Adhikary
Michael Dingfelder
Miral Dizdaroglu
Greenville College · USNational Institute of Standards and Technology · USNational University of Singapore · SGOakland University · US

Funding

RADIOPROTECTION OF DNA BY THIOLS--OXYGEN AND LET EFFECTSR01CA045424 · NCI · OAKLAND UNIVERSITY · PI SEVILLA, MICHAEL DOUGLAS · 1987 to 2021
$4.2M
NCI NIH HHS R01 CA045424
6 · The paper itself

Abstract

Recent publications have suggested that oxidative DNA damage mediated by hydroxyl radical (˙OH) is unimportant in vivo, and that carbonate anion radical (CO

Indexed as

DNA DamageOxidative StressCarbonatesDNAHydroxyl RadicalOxidation-ReductionReactive Oxygen SpeciesCarbonatesDNAHydroxyl RadicalReactive Oxygen Species

Identifiers

PMID34128512
PMCPMC8328964
OpenAlexW3169592085

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.