Evidence map›Paper›PMID 34128130›Full record

SynthesisClinical oral investigations2021

Systematic review and meta-analysis of diagnostic methods for occlusal surface caries.

Svetlana Kapor, Mila Janjic Rankovic, Yegane Khazaei, Alexander Crispin, Ina Schüler, Felix Krause, Adrian Lussi, Klaus Neuhaus, Florin Eggmann, Stavroula Michou and 3 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Herbal medicines to prevent dental caries.The Cochrane database of systematic reviews · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Svetlana KaporDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilian University, Munich, Germany.
Mila Janjic RankovicDepartment of Orthodontics and Dentofacial Orthopedics, University Hospital, Ludwig-Maximilian Universität München, Munich, Germany.
Yegane KhazaeiDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilian University, Munich, Germany.
Alexander CrispinInstitute of Medical Biometry and Epidemiology, Ludwig-Maximilian University of Munich, Munich, Germany.
Ina SchülerDepartment of Orthodontics, Section of Preventive and Paediatric Dentistry, University Hospital, Jena, Germany.
Felix KrauseClinic for Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital RWTH Aachen, Aachen, Germany.
Adrian LussiDepartment of Operative Dentistry and Periodontology, Faculty of Dentistry, University Medical Centre, Freiburg, Germany.
Klaus NeuhausClinic of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine Basel, University of Basel, Basel, Switzerland.
Florin EggmannClinic of Periodontology, Endodontology and Cariology, University Centre for Dental Medicine Basel, University of Basel, Basel, Switzerland.
Stavroula MichouDepartment of Odontology, University Copenhagen, Copenhagen, Denmark.
Kim EkstrandDepartment of Odontology, University Copenhagen, Copenhagen, Denmark.
Marie-Charlotte HuysmansDepartment of Dentistry, Radboud University Medical Centre, Nijmegen, the Netherlands.
Jan KühnischDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilian University, Munich, Germany. jkuehn@dent.med.uni-muenchen.de.ORCID http://orcid.org/0000-0003-4063-2291

Funding

Deutsche Forschungsgemeinschaft SCHU-3217/1-1
6 · The paper itself

Abstract

aimThis systematic review and meta-analysis aimed to assess the diagnostic performance of commonly used methods for occlusal caries diagnostics, such as visual examination (VE), bitewing radiography (BW) and laser fluorescence (LF), in relation to their ability to detect (dentin) caries under clinical and laboratory conditions. MATERIALS AND

methodsA systematic search of the literature was performed to identify studies meeting the inclusion criteria using the PIRDS concept (N = 1090). A risk of bias (RoB) assessment tool was used for quality evaluation. Reports with low/moderate RoB, well-matching thresholds for index and reference tests and appropriate reporting were included in the meta-analysis (N = 37; 29 in vivo/8 in vitro). The pooled sensitivity (SE), specificity (SP), diagnostic odds ratio (DOR) and areas under ROC curves (AUCs) were computed.

resultsSP ranged from 0.50 (fibre-optic transillumination/caries detection level) to 0.97 (conventional BW/dentine detection level) in vitro. AUCs were typically higher for BW or LF than for VE. The highest AUC of 0.89 was observed for VE at the 1/3 dentin caries detection level; SE (0.70) was registered to be higher than SP (0.47) for VE at the caries detection level in vivo.

conclusionThe number of included studies was found to be low. This underlines the need for high-quality caries diagnostic studies that further provide data in relation to multiple caries thresholds. CLINICAL RELEVANCE: VE, BW and LF provide acceptable measures for their diagnostic performance on occlusal surfaces, but the results should be interpreted with caution due to the limited data in many categories.

Indexed as

Dental CariesDental Caries SusceptibilityFluorescenceHumansRadiography, BitewingReproducibility of ResultsSensitivity and SpecificityTransilluminationAccuracyBitewing radiographyCaries detectionCaries diagnosticsDiagnostic performanceFibre-optic transilluminationLaser fluorescence measurementsMeta-analysisOcclusal cariesPit and fissure cariesSensitivitySpecificitySystematic reviewVisual examination

Identifiers

PMID34128130
PMCPMC8342337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.