Evidence map›Paper›PMID 34127980›Full record

ArticlemedRxiv : the preprint server for health sciences2021

2020 SARS-CoV-2 diversification in the United States: Establishing a pre-vaccination baseline.

Adam A Capoferri, Wei Shao, Jon Spindler, John M Coffin, Jason W Rausch, Mary F Kearney

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Adam A CapoferriHIV Dynamics and Replication Program, National Cancer Institute, Frederick, Maryland, USA.
Wei ShaoAdvanced Biomedical Computing Science, Frederick National Laboratory for Cancer Research (FNLCR) sponsored by the National Cancer Institute, Frederick, Maryland, USA.
Jon SpindlerHIV Dynamics and Replication Program, National Cancer Institute, Frederick, Maryland, USA.
John M CoffinDepartment of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts, USA.
Jason W RauschHIV Dynamics and Replication Program, National Cancer Institute, Frederick, Maryland, USA.
Mary F KearneyHIV Dynamics and Replication Program, National Cancer Institute, Frederick, Maryland, USA.

Funding

Retrovirus Evolution and CancerR35CA200421 · NCI · TUFTS UNIVERSITY BOSTON · PI COFFIN, JOHN M · 2016 to 2022
$6.5M
Assessment of SARS-Coronavirus-2 Levels and Genetics in VivoZIABC011995 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KEARNEY, MARY · 2020 to 2022
$628k
NCI NIH HHS R35 CA200421
6 · The paper itself

Abstract

In 2020, SARS-CoV-2 spread across the United States (U.S.) in three phases distinguished by peaks in the numbers of infections and shifting geographical distribution. We investigated the viral genetic diversity in each phase using sequences publicly available prior to December 15 ONE SENTENCE SUMMARY: SARS-CoV-2 genetic diversity in the U.S. increased 3-fold in 2020 and 54 emergent nonsynonymous mutations were detected.

Identifiers

PMID34127980
PMCPMC8202437

What OpenQuestion holds

Textmetadata
LicenceCC0
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.