Evidence map›Paper›PMID 34127622›Full record

ReviewCurrent opinion in pulmonary medicine2021

At a crossroads: coronavirus disease 2019 recovery and the risk of pulmonary vascular disease.

Thomas M Cascino, Ankit A Desai, Yogendra Kanthi

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Thomas M CascinoFrankel Cardiovascular Center, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.
Ankit A DesaiDepartment of Medicine, Indiana University, Indianapolis, Indiana.
Yogendra KanthiFrankel Cardiovascular Center, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.
Ann Arbor VA Medical Center · USIndiana University – Purdue University Indianapolis · USMichigan Medicine · US

Funding

Human Translational Studies of Vascular Thrombosis and InflammationZIAHL006262 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KANTHI, YOGENDRA · 2021 to 2025
$4.7M
Vascular Immunobiology Mechanistic and Translational StudiesZIAHL006267 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KANTHI, YOGENDRA · 2021 to 2025
$4.6M
Unraveling Cytotoxic and Thrombotic Signals in Host-defense ResponsesZIAHL006263 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KANTHI, YOGENDRA · 2021 to 2025
$3.5M
Pathogenic Role of IL-18 in Sickle Cell Cardiomyopathy and Inducible Ventricular TachycardiaR01HL136603 · NHLBI · UNIVERSITY OF ARIZONA · PI DESAI, ANKIT A · 2017 to 2021
$2.4M
Intramural NIH HHS Z99 HL999999NHLBI NIH HHS R01 HL136603
6 · The paper itself

Abstract

purpose of reviewThe coronavirus disease 2019 (COVID-19) pandemic has led to almost 3,000,000 deaths across 139 million people infected worldwide. Involvement of the pulmonary vasculature is considered a major driving force for morbidity and mortality. We set out to summarize current knowledge on the acute manifestations of pulmonary vascular disease (PVD) resulting from COVID-19 and prioritize long-term complications that may result in pulmonary hypertension (PH). RECENT

findingsAcute COVID-19 infection can result in widespread involvement of the pulmonary vasculature, myocardial injury, evidence of persistent lung disease, and venous thromboembolism. Post COVID-19 survivors frequently report ongoing symptoms and may be at risk for the spectrum of PH, including group 1 pulmonary arterial hypertension, group 2 PH due to left heart disease, group 3 PH due to lung disease and/or hypoxia, and group 4 chronic thromboembolic PH. SUMMARY: The impact of COVID-19 on the pulmonary vasculature is central to determining disease severity. Although the long-term PVD manifestations of COVID-19 are currently uncertain, optimizing the care of risk factors for PH and monitoring for the development of PVD will be critical to reducing long-term morbidity and improving the health of survivors.

Indexed as

COVID-19Lung DiseasesVascular DiseasesHumansPandemicsPulmonary CirculationSARS-CoV-2

Identifiers

PMID34127622
PMCPMC8373709
OpenAlexW3166572335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.