Evidence map›Paper›PMID 34126996›Full record

Trial reportJournal of the International Society of Sports Nutrition2021

Broad Spectrum Polyphenol Supplementation from Tart Cherry Extract on Markers of Recovery from Intense Resistance Exercise.

D R Hooper, T Orange, M T Gruber, A A Darakjian, K L Conway, H A Hausenblas

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06332222 nacompletednot on this mapstarted 2023, after this paper: background citation

Recovery With Tart Cherry Supplementation Following a Marathon.

TypeinterventionalSponsorNorthumbria UniversityRan2023 to 2023Enrolled35ConditionsExercise RecoveryArmsTart Cherry, Placebo
NCT06790771 nacompletednot on this mapstarted 2025, after this paper: background citation

Acute Effect of Supplement Containing L-Arginine on Appetite Suppression and GLP-1 Induction

TypeinterventionalSponsorTexas Christian UniversityRan2025 to 2026Enrolled25ConditionsHungerArmsHigh Dose Supplement, Low Dose Supplement, Placebo
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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  17. Effects of a Tart Cherry Supplement on Recovery from Exhaustive Exercise.Journal of functional morphology and kinesiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

D R HooperCenter for Health and Human Performance, Jacksonville University, Jacksonville, USA. dhooper4@ju.edu.ORCID http://orcid.org/0000-0002-6610-6583
T OrangeCenter for Health and Human Performance, Jacksonville University, Jacksonville, USA.
M T GruberDepartment of Biology and Marine Science, Jacksonville University, Jacksonville, USA.
A A DarakjianDepartment of Biology and Marine Science, Jacksonville University, Jacksonville, USA.
K L ConwayDepartment of Biology and Marine Science, Jacksonville University, Jacksonville, USA.
H A HausenblasCenter for Health and Human Performance, Jacksonville University, Jacksonville, USA.
Jacksonville University · USUniversity of Florida Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTart cherry supplementation has been shown to enhance recovery from strenuous exercise due to its antioxidant properties. The majority of these studies used tart cherry juice, with a significant calorie content. The primary purpose of this study was to assess whether powdered tart cherry extract with minimal calorie content reduces oxidative stress and enhances recovery following intense resistance exercise.

methodsThirteen men (mean age: 26.2 ± 5.3 years; height: 184.3 ± 8.2 cm; weight: 92.9 ± 15.6 kg) performed a demanding resistance exercise protocol consisting of 6 sets of 10 repetitions of barbell back squat with 80% 1RM. The protocol was performed once following 7 days of 500 mg of tart cherry extract and once following placebo. Serum protein carbonyl (PC) content, creatine kinase activity (CK) and creatine kinase myocardial band content (CK-MB) were used to assess oxidative stress, skeletal and cardiac muscle damage respectively. Muscle soreness was assessed by visual analog scale. Physical performance was measured by countermovement jump power and handgrip dynamometer strength.

resultsThere was a significant increase in PC in the placebo (PL) condition when compared to the Tart Cherry (TC) condition at Immediate Post (IP) (PL: 0.4 ± 0.3 vs. TC: - 0.4 ± 0.2 nmol∙mg

conclusionsThis study demonstrated that tart cherry extract reduced oxidative stress and markers of muscle and cardiac damage following intense resistance exercise. This occurred along with a prevention of the decrease in handgrip strength seen following the intense exercise protocol, indicating a potential reduction in central fatigue. These benefits were seen with minimal energy intake.

Indexed as

Dietary SupplementsAdultBiomarkersCreatine KinaseCreatine Kinase, MB FormCross-Over StudiesHand StrengthHumansMaleMuscle FatigueMuscle, SkeletalMyalgiaOxidative StressPlant ExtractsPolyphenolsProtein CarbonylationBiomarkersCreatine KinaseCreatine Kinase, MB FormPlant ExtractsPolyphenolsantioxidantscardiac damagemuscle damagepolyphenolsrecoveryTart cherry

Identifiers

PMID34126996
PMCPMC8204440
OpenAlexW3158700740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.