Evidence map›Paper›PMID 34126949›Full record

ArticleBMC cancer2021

Surgical and functional outcomes and survival following Colon Cancer surgery in the aged: a study protocol for a prospective, observational multicentre study.

Susanna Niemeläinen, Heini Huhtala, Anu Ehrlich, Jyrki Kössi, Esa Jämsen, Marja Hyöty

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03904121 (Colon Cancer Surgery in the Aged; Postoperative Outcome, Functional Recovery and Survival), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03904121 completednot on this map

Colon Cancer Surgery in the Aged; Postoperative Outcome, Functional Recovery and Survival

Typeobservational_patient_registrySponsorTampere University HospitalRan2019 to 2022Enrolled262ConditionsColon CancerArmsCurative operation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Clinical Frailty Scale predicts overall survival after colon cancer surgery in people aged 80 years and older: A prospective multicentre observational study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Observational
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Susanna NiemeläinenDepartment of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tays Hatanpää, P.O. Box 2000, 33521, Tampere, Finland. susanna.niemelainen@pshp.fi.ORCID http://orcid.org/0000-0003-1910-2640
Heini HuhtalaFaculty of Social Sciences, Tampere University, Tampere, Finland.
Anu EhrlichJorvi Hospital, Helsinki University Hospital, Helsinki, Finland.
Jyrki KössiPäijät-Häme Central Hospital, Lahti, Finland.
Esa JämsenTampere University Hospital, Centre of Geriatrics, Tampere, Finland.
Marja HyötyDepartment of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tays Hatanpää, P.O. Box 2000, 33521, Tampere, Finland.
Tampere University · FITampere University Hospital · FIHelsinki University Hospital · FIPäijät-Hämeen Keskussairaala · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of colorectal cancer patients increases with age. The decision to go through major surgery can be challenging for the aged patient and the surgeon because of the heterogeneity within the older population. Differences in preoperative physical and cognitive status can affect postoperative outcomes and functional recovery, and impact on patients' quality of life. METHODS /

designA prospective, observational, multicentre study including nine hospitals to analyse the impact of colon cancer surgery on functional ability, short-term outcomes (complications and mortality), and their predictors in patients aged ≥80 years. The catchment area of the study hospitals is 3.88 million people, representing 70% of the population of Finland. The data will be gathered from patient baseline characteristics, surgical interventional data, and pre- and postoperative patient-questionnaires, to an electronic database (REDCap) especially dedicated to the study. DISCUSSION: This multicentre study provides information about colon cancer surgery's operative and functional outcomes on older patients. A further aim is to find prognostic factors which could help to predict adverse outcomes of surgery.

trial registrationClinicalTrials.gov ( NCT03904121 ). Registered on 1 April 2019.

Indexed as

Aged, 80 and overColonic NeoplasmsFemaleHumansMaleProspective StudiesSurvival AnalysisAged patientsColon cancerFunctional ability, short-term outcomeSurgery

Identifiers

PMID34126949
PMCPMC8201898
OpenAlexW3170248252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.