Evidence map›Paper›PMID 34126772›Full record

ArticlemBio2021

Reactive Oxygen Species-Dependent Innate Immune Mechanisms Control Methicillin-Resistant Staphylococcus aureus Virulence in the

Elodie Ramond, Anne Jamet, Xiongqi Ding, Daniel Euphrasie, Clémence Bouvier, Louison Lallemant, Xiangyan He, Laurence Arbibe, Mathieu Coureuil, Alain Charbit

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  9. Article
  10. Infection and immunity · 2023
    Review
  11. Article
  12. Repression ofMicroorganisms · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Elodie RamondUniversité de Paris, Paris, France.
Anne JametUniversité de Paris, Paris, France.
Xiongqi DingUniversité de Paris, Paris, France.
Daniel EuphrasieUniversité de Paris, Paris, France.
Clémence BouvierUniversité de Paris, Paris, France.
Louison LallemantCell Imaging Core Facility, Structure Fédérative de Recherche Necker, INSERM US24/CNRS UMS3633, Paris, France.
Xiangyan HeUniversité de Paris, Paris, France.
Laurence ArbibeUniversité de Paris, Paris, France.
Mathieu CoureuilUniversité de Paris, Paris, France.
Alain CharbitUniversité de Paris, Paris, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic-resistant Staphylococcus aureus strains constitute a major public health concern worldwide and are responsible for both health care- and community-associated infections. Here, we establish a robust and easy-to-implement model of oral S. aureus infection using Drosophila melanogaster larvae that allowed us to follow the fate of S. aureus at the whole-organism level as well as the host immune responses. Our study demonstrates that S. aureus infection triggers H

Indexed as

Immunity, InnateAnimalsDisease Models, AnimalDrosophila melanogasterGene Expression Regulation, BacterialHost-Pathogen InteractionsLarvaMethicillin-Resistant Staphylococcus aureusPore Forming Cytotoxic ProteinsReactive Oxygen SpeciesStaphylococcal InfectionsVirulencePore Forming Cytotoxic ProteinsReactive Oxygen SpeciescatalaseDrosophila melanogasterDuoxgastrointestinal infectionintestinal infectionStaphylococcus aureusvirulence

Identifiers

PMID34126772
PMCPMC8262968
OpenAlexW3171012754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.