Evidence map›Paper›PMID 34126579›Full record

Observational studyRespiratory medicine

Symptoms in patients with asthma infected by SARS-CoV-2.

Eduardo Garcia-Pachon, Sandra Ruiz-Alcaraz, Carlos Baeza-Martinez, Lucia Zamora-Molina, Maria J Soler-Sempere, Isabel Padilla-Navas, Justo Grau-Delgado

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Respiratory medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Lung function before and after COVID-19 in young adults: A population-based study.The journal of allergy and clinical immunology. Global · 2022
    Article
  6. Article
  7. Asthma as a risk factor for hospitalization in children with COVID-19: A nested case-control study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Eduardo Garcia-PachonSection of Respiratory Medicine, Hospital General Universitario de Elche, Elche, Alicante, Spain. Electronic address: egpachon@gmail.com.
Sandra Ruiz-AlcarazSection of Respiratory Medicine, Hospital General Universitario de Elche, Elche, Alicante, Spain.
Carlos Baeza-MartinezSection of Respiratory Medicine, Hospital General Universitario de Elche, Elche, Alicante, Spain.
Lucia Zamora-MolinaSection of Respiratory Medicine, Hospital General Universitario de Elche, Elche, Alicante, Spain.
Maria J Soler-SempereSection of Respiratory Medicine, Hospital General Universitario de Elche, Elche, Alicante, Spain.
Isabel Padilla-NavasSection of Respiratory Medicine, Hospital General Universitario de Elche, Elche, Alicante, Spain.
Justo Grau-DelgadoSection of Respiratory Medicine, Hospital General Universitario de Elche, Elche, Alicante, Spain.
Hospital General Universitario de Elche · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOrgan tropism of SARS-CoV-2 to the respiratory tract could potentially aggravate asthma. The susceptibility of patients with asthma to develop an exacerbation when they are infected with SARS-CoV-2 is unknown. We aimed to investigate the symptoms presented in patients with asthma who became infected with SARS-CoV-2. METHODS AND

resultsAll patients over 14 years of age who tested positive for SARS-CoV-2 (by RT-PCR) were included (n = 2995). In patients with asthma (n = 77, 2.6%; 44 females), symptoms, therapy and phenotype were recorded. Seventeen (22%) patients had mild asthma, 55 (71%) moderate and five severe (6%). Twenty-six patients with asthma (34%) were asymptomatic, 34 (44%) developed symptoms but did not require hospital admission, and 17 (22%) were hospitalised. One patient was admitted because of asthma exacerbation without pneumonia or other symptoms. Ten patients (13%) had wheezes (six with pneumonia). Comparison of wheezing between patients with non-T2 asthma and the rest of the patients was statistically significant, (p < 0.001).

conclusionsSARS-CoV-2 infection is not a significant cause of asthma exacerbation, although some patients may present wheezing, especially in cases of pneumonia. The severity of asthma does not seem to be associated with symptoms of the disease.

Indexed as

SARS-CoV-2AdultAsthmaComorbidityCOVID-19FemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexAsthmaCovid-19Virus

Identifiers

PMID34126579
PMCPMC8184356
OpenAlexW3168072805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.