Evidence map›Paper›PMID 34125595›Full record

ArticleAntimicrobial agents and chemotherapy2021

Mutations in a Membrane Permease or

Denny Chin, Mariya I Goncheva, Ronald S Flannagan, David E Heinrichs

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Denny ChinDepartment of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada.
Mariya I GonchevaDepartment of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada.
Ronald S FlannaganDepartment of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada.
David E HeinrichsDepartment of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada.
Western University · CA

Funding

Gouvernement du Canada | Canadian Institutes of Health Research (CIHR) PJT-153308
6 · The paper itself

Abstract

We recently discovered that 6-thioguanine (6-TG) is an antivirulence compound that is produced by a number of coagulase-negative staphylococci. In Staphylococcus aureus, it inhibits

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsMembrane Transport ProteinsMiceMutationStaphylococcus aureusThioguanineAnti-Bacterial AgentsMembrane Transport ProteinsThioguanineantivirulenceguanine analogMRSAresistance

Identifiers

PMID34125595
PMCPMC8370250
OpenAlexW3167801050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.