Evidence map›Paper›PMID 34125583›Full record

ArticleEcoSal Plus2021

Salmonella Genomics in Public Health and Food Safety.

Eric W Brown, Rebecca Bell, Guodong Zhang, Ruth Timme, Jie Zheng, Thomas S Hammack, Marc W Allard

Abstract read
In one paragraph

Article in EcoSal Plus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Establishment of methods for the detection ofVeterinary and animal science · 2026
    Article
  3. Article
  4. Microbial genomics · 2026
    Article
  5. Assessing transcriptomic responses ofMicrobiology spectrum · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Infection biology ofEcoSal Plus · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Unveiling the genomic landscape ofMicrobiology spectrum · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eric W BrownCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Rebecca BellCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Guodong ZhangCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Ruth TimmeCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.ORCID 0000-0002-9705-5897
Jie ZhengCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.ORCID 0000-0003-3447-9681
Thomas S HammackCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Marc W AllardCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The species Salmonella enterica comprises over 2,600 serovars, many of which are known to be intracellular pathogens of mammals, birds, and reptiles. It is now apparent that Salmonella is a highly adapted environmental microbe and can readily persist in a number of environmental niches, including water, soil, and various plant (including produce) species. Much of what is known about the evolution and diversity of nontyphoidal Salmonella serovars (NTS) in the environment is the result of the rise of the genomics era in enteric microbiology. There are over 340,000 Salmonella genomes available in public databases. This extraordinary breadth of genomic diversity now available for the species, coupled with widespread availability and affordability of whole-genome sequencing (WGS) instrumentation, has transformed the way in which we detect, differentiate, and characterize Salmonella enterica strains in a timely way. Not only have WGS data afforded a detailed and global examination of the molecular epidemiological movement of Salmonella from diverse environmental reservoirs into human and animal hosts, but they have also allowed considerable consolidation of the diagnostic effort required to test for various phenotypes important to the characterization of Salmonella. For example, drug resistance, serovar, virulence determinants, and other genome-based attributes can all be discerned using a genome sequence. Finally, genomic analysis, in conjunction with functional and phenotypic approaches, is beginning to provide new insights into the precise adaptive changes that permit persistence of NTS in so many diverse and challenging environmental niches.

Indexed as

Public HealthSalmonellaAnimalsFood SafetyGenomicsHumansPhylogenyadaptive changedata sharingepidemiologyfoodborne pathogen isolatesgenomic impactmicrobiologynontyphoidal salmonellaeontologySalmonella detectionwhole-genome sequencing

Identifiers

PMID34125583
PMCPMC11163839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.