Evidence map›Paper›PMID 34125189›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022

Perceived Discrimination, Nativity, and Cognitive Performance in a Multiethnic Study of Older Adults: Findings From the Kaiser Healthy Aging and Diverse Life Experiences Study.

Erika Meza, Rachel Peterson, Paola Gilsanz, Kristen M George, Sunita J Miles, Chloe W Eng, Dan M Mungas, Elizabeth Rose Mayeda, M Maria Glymour, Rachel A Whitmer

Open access · bronzeAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Do white matter hyperintensities account for the relationship between discrimination and memory?Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  5. Beyond Acculturation: Contextual Factors Predicting Neurocognitive Performance in a Clinical Sample of Latina/o/e Adults.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025
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  8. Cognitive Performance of Latino and White Non-Latino Individuals With Parkinson's Disease.The Journal of neuropsychiatry and clinical neurosciences · 2025
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  12. Discrimination and Cognition in Midlife Black Women: The Roles of Social Support and Spirituality.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  13. The Effects of Midlife Acute and Chronic Stressors on Black-White Differences in Cognitive Decline.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Erika MezaDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Rachel PetersonDepartment of Public Health Sciences, University of California, Davis, USA.ORCID 0000-0001-6818-7009
Paola GilsanzDivision of Research, Kaiser Permanente Northern California, Oakland, USA.ORCID 0000-0002-7635-381X
Kristen M GeorgeDepartment of Public Health Sciences, University of California, Davis, USA.ORCID 0000-0001-8773-7678
Sunita J MilesDivision of Research, Kaiser Permanente Northern California, Oakland, USA.
Chloe W EngDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Dan M MungasDepartment of Neurology, University of California, Davis, USA.
Elizabeth Rose MayedaDepartment of Epidemiology, University of California, Los Angeles Fielding School of Public Health, USA.
M Maria GlymourDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Rachel A WhitmerDepartment of Public Health Sciences, University of California, Davis, USA.
Kaiser Permanente · USUniversity of California, Davis · USUniversity of California, San Francisco · USUniversity of California, Los Angeles · US

Funding

UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEE-WAY JIN · 2021 to 2026
$25.2M
Lifecourse health, cerebral pathology and ethnic disparities in dementia (KHANDLE Study)R01AG052132 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GILSANZ, PAOLA, GLYMOUR, MEDELLENA MARIA · 2021 to 2025
$18.0M
Lifecourse health, cerebral pathology and ethnic disparities in dementiaRF1AG052132 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DECARLI, CHARLES, GLYMOUR, MEDELLENA MARIA · 2016 to 2016
$13.1M
Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HIRAM BELTRAN-SANCHEZ · 2016 to 2026
$6.9M
Translational Epidemiology - Training for Research on Aging and Chronic diseaseT32AG049663 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Elizabeth Rose Mayeda, Mark J Pletcher · 2016 to 2026
$5.8M
Alzheimer's AssociationNIA NIH HHS P30 AG072972NIA NIH HHS R01 AG052132NIA NIH HHS RF1 AG052132NIA NIH HHS T32 AG049663NICHD NIH HHS P2C HD041022
6 · The paper itself

Abstract

backgroundDespite growing research on the association between discrimination and disparities in cognitive aging, an evidence gap remains on how the association varies by racial/ethnic group. This study evaluates the associations of experiences of discrimination with cognitive function and whether these associations varied by race/ethnicity and nativity.

methodUsing the Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) cohort (N = 1 712) with approximately equal groups of Black, White, Latino, and Asian community-dwelling older adults aged 65 years and older, we evaluated the associations between self-reported experiences of everyday and major lifetime discrimination with overall cognitive performance and domain-specific cognition (verbal episodic memory, semantic memory, and executive functioning) across race/ethnicity and nativity. Linear regression models examined the cross-sectional association between self-reported experiences of everyday and major lifetime discrimination with z-standardized coefficients for cognition. We tested for effect modification by race and nativity. All models controlled for age, sex, and education.

resultsAmong KHANDLE participants (mean age: 76 years; SD: 6.8), everyday discrimination was not associated with cognitive scores. Major lifetime discrimination was associated with better average cognitive scores among Black participants but not among other racial/ethnic groups. Major lifetime discrimination was associated with better average cognitive scores among U.S.-born but not among non-U.S.-born individuals.

conclusionOur findings do not imply that discrimination improves cognition, but rather suggest that future research should include more detailed measures on discrimination and unfair treatment that could help disentangle the extent to which relationships are causal or reflect some other underlying factor.

Indexed as

Healthy AgingAgedCognitionCross-Sectional StudiesHumansLife Change EventsPerceived DiscriminationCognitive agingEpidemiologyHealth disparitiesMinority aging

Identifiers

PMID34125189
PMCPMC8824601
OpenAlexW3171789528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.