ArticleThe western journal of emergency medicine2021
Universal Screening for Hepatitis C Virus in the ED Using a Best Practice Advisory.
Article in The western journal of emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Non-risk-based HCV screening at point of care: a prospective pilot.BMC infectious diseases · 2026Article
- Development and Validation of a Machine Learning-Based Screening Algorithm to Predict High-Risk Hepatitis C Infection.Open forum infectious diseases · 2025Article
- A scoping review on HCV screening strategies: population to screen and the test types.BMC public health · 2025Article
- Validating an Electronic Health Record Algorithm for Diabetes Screening Eligibility in the Emergency Department.The western journal of emergency medicine · 2025Article
- Enhancing Hepatitis C Virus Testing, Linkage to Care, and Treatment Commencement in Hospitals: A Systematic Review and Meta-analysis.Open forum infectious diseases · 2025Article
- Nursing health technologies in the prevention and control of hepatitis A: a scoping review.Revista da Escola de Enfermagem da U S P · 2025Article
- Opportunities for Enhanced Prevention and Control of Hepatitis C Through Improved Screening and Testing Efforts.The Journal of infectious diseases · 2024Article
- Sexually Transmitted Infection Co-testing in a Large Urban Emergency Department.The western journal of emergency medicine · 2024Article
- Implementation of geriatric screening in the emergency department using the Consolidated Framework for Implementation Research.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2023Article
- Assessment of a COVID-19 vaccination protocol for unhoused patients in the emergency department.Vaccine · 2023Article
- HCV universal EHR prompt successfully increases screening, highlights potential disparities.PloS one · 2023Article
- Aligning an emergency department hepatitis C and human immunodeficiency virus testing quality improvement initiative with universal screening recommendations.Journal of the American College of Emergency Physicians open · 2022Article
- Sustained Impact of the Coronavirus Disease 2019 Pandemic on Hepatitis C Virus Treatment Initiations in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department.The western journal of emergency medicine · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn 2019 the United States Preventive Services Task Force (USPSTF) released draft guidelines recommending universal hepatitis C virus (HCV) screening for individuals aged 18-79. We aimed to assess the efficacy of an emergency department-based HCV screening program, by comparing screening practices before and after its implementation.
methodsWe performed a retrospective cohort analysis of two temporally matched, 11-month study periods, corresponding to before and after the implementation of a best practice advisory (BPA). Patients were screened for anti-HCV antibody (Ab), and positive results were followed by HCV viral load (VL) testing. The primary implementation outcome was ED testing volume (number of tests performed/month). The primary screening outcomes were the seroprevalence of anti-HCV Ab and HCV VL. We describe data with simple descriptive statistics.
resultsThe median age of patients was similar between periods (pre: 50 years [interquartile range [IQR] 34-62], post: 47 years [IQR 33-59]). Patients screened were more likely to be males in the pre-BPA period (Male, pre: 60%, post: 49%). During the pre-BPA study period, a total of 69,604 patients were seen in the ED, and 218 unique patients were screened for HCV (mean 19.8 tests/month). During the post-BPA study period, a total of 68,225 patients were seen in the ED, and 14,981 unique patients were screened for HCV (mean 1361.9 tests/month). Anti-HCV Ab seroprevalence was 23% (51/218) and 9% (1340/14,981) in the pre-BPA and post-BPA periods, respectively. In the pre-BPA period, six patients with a positive anti-HCV Ab level had follow-up VL testing (detectable in three). In the post-BPA period, reflex VL testing was performed in most patients (91%, 1225/1,340), and there were 563 patients with detectable VLs, indicating active infection.
conclusionOur study shows that using a universal BPA-driven screening protocol can dramatically increase the number of patients screened for HCV and increase the number of new HCV diagnoses.
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