Evidence map›Paper›PMID 34124973›Full record

SynthesisAnnals of medicine2021

The pattern of human papillomavirus infection and genotypes among Nigerian women from 1999 to 2019: a systematic review.

Anthony Uchenna Emeribe, Idris Nasir Abdullahi, Maisie Henrietta Etukudo, Idongesit Kokoabasi Isong, Anthony Ogbonna Emeribe, Justin Onyebuchi Nwofe, Chikodi Modesta Umeozuru, Buhari Isa Shuaib, Odunayo Rahmat Oyetola Ajagbe, Amos Dangana and 2 more

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Anthony Uchenna EmeribeDepartment of Medical Laboratory Science, Faculty of Allied Medical Sciences, University of Calabar, Calabar, Nigeria.ORCID 0000-0003-2937-8595
Idris Nasir AbdullahiDepartment of Medical Laboratory Science, Faculty of Allied Health Sciences, Ahmadu Bello University, Zaria, Nigeria.ORCID 0000-0002-5511-1272
Maisie Henrietta EtukudoDepartment of Medical Laboratory Science, Faculty of Allied Medical Sciences, University of Calabar, Calabar, Nigeria.ORCID 0000-0002-4997-6245
Idongesit Kokoabasi IsongDepartment of Medical Laboratory Science, Faculty of Allied Medical Sciences, University of Calabar, Calabar, Nigeria.ORCID 0000-0002-6943-6174
Anthony Ogbonna EmeribeDepartment of Medical Laboratory Science, Faculty of Allied Medical Sciences, University of Calabar, Calabar, Nigeria.
Justin Onyebuchi NwofeDepartment of Medical Laboratory Science, Ebonyi State University, Abakaliki, Nigeria.ORCID 0000-0001-7598-5228
Chikodi Modesta UmeozuruNigeria Field Epidemiology and Laboratory Training Programme, African Field Epidemiology Network, Abuja, Nigeria.ORCID 0000-0001-5629-6929
Buhari Isa ShuaibAntiretroviral Therapy Laboratory, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.ORCID 0000-0003-0147-4884
Odunayo Rahmat Oyetola AjagbeSolina International Center for Research and Development, Abuja, Nigeria.ORCID 0000-0002-8315-3437
Amos DanganaDepartment of Medical Laboratory Services, University of Abuja Teaching Hospital, Abuja, Nigeria.
Bibiana Nonye EgentiDepartment of Community Medicine, University of Abuja, Abuja, Nigeria.
Peter Elisha GhambaWHO National Polio Reference Laboratory, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria.ORCID 0000-0001-5596-6759
University of Calabar · NGAfrican Field Epidemiology Network · NGAhmadu Bello University · NGAhmadu Bello University Teaching Hospital · NGDepartment for International Development · GBEbonyi State University · NGUniversity of Abuja · NGUniversity of Abuja Teaching Hospital · NGUniversity of Maiduguri · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are no robust national prevalence of Human Papillomavirus (HPV) genotypes in Nigerian women despite the high burden of cervical cancer morbidity and mortality. THE OBJECTIVE OF STUDY: This study aims to determine the pooled prevalence and risk factors of genital HPV infection in Nigeria through a systemic review protocol.

methodsDatabases including PubMed, Scopus, Google Scholar and AJOL were searched between 10 April to 28 July 2020. HPV studies on Nigerian females and published from April 1999 to March 2019 were included. GRADE was used to assess the quality of evidence.

resultsThe pooled prevalence of cervical HPV was 20.65% (95%CI: 19.7-21.7). Genotypes 31 (70.8%), 35 (69.9%) and 16 (52.9%) were the most predominant HPV in circulation. Of the six geopolitical zones in Nigeria, northeast had the highest pooled prevalence of HPV infection (48.1%), while the least was in the north-west (6.8%). After multivariate logistic regression, duration (years) of sexual exposure (OR = 3.24, 95%CI: 1.78-9.23]), history of other malignancies (OR = 1.93, 95%CI: 1.03-2.97]), history of sexually transmitted infection (OR = 2.45, 95% CI: 1.31-3.55]), coital frequency per week (OR = 5.11, 95%CI: 3.86-14.29), the status of circumcision of the sexual partner (OR = 2.71, 95%CI: 1.62-9.05), and marital status (OR = 1.72, 95%CI: 1.16-4.72), were significant risk factors of HPV infection (

conclusionHPV prevalence is high in Nigeria and was significantly associated with several associated risk factors. Rapid screening for high-risk HPV genotypes is recommended and multivalent HPV vaccines should be considered for women.

Indexed as

GenotypePapillomavirus InfectionsUterine Cervical NeoplasmsFemaleHumansNigeriaPapillomaviridaePrevalencecervical cancerHPV genotypesHPV infectionNigeriapooled prevalencerisk factors

Identifiers

PMID34124973
PMCPMC8205070
OpenAlexW3166170161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.