Evidence map›Paper›PMID 34124877›Full record

ArticleACS applied materials & interfaces2021

3D-Printed Drug Capture Materials Based on Genomic DNA Coatings.

Daryl W Yee, Steven W Hetts, Julia R Greer

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Daryl W YeeDivision of Engineering and Applied Science, California Institute of Technology, Pasadena, California 91125, United States.ORCID https://orcid.org/0000-0002-4114-6167
Steven W HettsDepartment of Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, California 94107, United States.
Julia R GreerDivision of Engineering and Applied Science, California Institute of Technology, Pasadena, California 91125, United States.ORCID https://orcid.org/0000-0002-9675-1508
California Institute of Technology · USUniversity of California, San Francisco · US

Funding

Endovascular Magnetic Catheter for Interventional MRIR01EB012031 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM, MARTIN, ALASTAIR J · 2011 to 2021
$4.8M
Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce ToxicityR01CA194533 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM · 2015 to 2019
$2.6M
NCI NIH HHS R01 CA194533NIBIB NIH HHS R01 EB012031
6 · The paper itself

Abstract

The toxic side effects of chemotherapy have long limited its efficacy, prompting expensive and long-drawn efforts to develop more targeted cancer therapeutics. An alternative approach to mitigate off-target toxicity is to develop a device that can sequester chemotherapeutic agents from the veins that drain the target organ before they enter systemic circulation. This effectively localizes the chemotherapy to the target organ, minimizing any hazardous side effects. 3D printing is ideal for fabricating these devices, as the geometric control afforded allows us to precisely dictate its hemodynamic performance

Indexed as

Acrylic ResinsAntineoplastic AgentsDNADoxorubicinHumansImmobilized Nucleic AcidsPrinting, Three-DimensionalAcrylic ResinsAntineoplastic AgentsDNADoxorubicinImmobilized Nucleic Acids3D printingchemotherapydrug capturegenomic DNAstimuli-responsivesurface coating

Identifiers

PMID34124877
PMCPMC11232429
OpenAlexW3169212729

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.