Evidence map›Paper›PMID 34124743›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2022

The Cardiovascular Cost of Silence: Relationships Between Self-silencing and Carotid Atherosclerosis in Midlife Women.

Karen P Jakubowski, Emma Barinas-Mitchell, Yue-Fang Chang, Pauline M Maki, Karen A Matthews, Rebecca C Thurston

Open access · greenAbstract read
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karen P JakubowskiDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-0936-5930
Emma Barinas-MitchellDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-7280-7781
Yue-Fang ChangDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, PA, USA.
Pauline M MakiDepartments of Psychiatry, Psychology and OB/GYN, University of Illinois at Chicago, Chicago, IL, USA.
Karen A MatthewsDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Rebecca C ThurstonDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USUniversity of Illinois Chicago · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
CARDIOVASCULAR BEHAVIORAL MEDICINE RESEARCH TRAININGT32HL007560 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Peter J Gianaros, REBECCA C THURSTON · 1985 to 2026
$11.3M
CLINICAL RESEARCH TRAINING FOR PSYCHOLOGISTST32MH018269 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MICHELE D LEVINE · 1986 to 2026
$6.3M
Translational Research Training in Sleep MedicineT32HL082610 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Daniel J. Buysse, PETER L FRANZEN · 2007 to 2026
$5.8M
Mechanisms linking hot flashes to cardiovascular riskR01HL105647 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI THURSTON, REBECCA C · 2011 to 2015
$3.2M
Interdisciplinary Mentoring and Research in Womens Cardiovascular HealthK24HL123565 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI THURSTON, REBECCA C · 2014 to 2023
$1.0M
NCATS NIH HHS UL1 TR000005NHLBI NIH HHS K24 HL123565NHLBI NIH HHS R01 HL105647NHLBI NIH HHS T32 HL007560NHLBI NIH HHS T32 HL082610NIMH NIH HHS T32 MH018269
6 · The paper itself

Abstract

backgroundIndividuals engage in a range of behaviors to maintain close relationships. One behavior is self-silencing or inhibiting self-expression to avoid relationship conflict or loss. Self-silencing is related to poor mental health and self-reported physical health in women but has not been examined in relation to cardiovascular health, particularly using direct measures of the vasculature. PURPOSE: To test associations between self-silencing and carotid atherosclerosis in midlife women; secondary analyses examined moderation by race/ethnicity.

methodsWomen (N = 290, ages 40-60) reported on self-silencing in intimate relationships and underwent physical measurements, blood draw, and ultrasound assessment of carotid intima-media thickness (IMT) and plaque. Associations between self-silencing and mean IMT and plaque index (0, 1, ≥2) were tested in linear regression and multinomial logistic regression models, respectively, followed by interaction terms between self-silencing and race, adjusted for demographic factors, CVD risk factors, partner status, depression, physical activity, and diet.

resultsForty-seven percent of women demonstrated carotid plaque. Greater self-silencing was related to increased odds of plaque index ≥2 (e.g., for each additional point, odds ratio [95% confidence interval] = 1.16 [1.03-1.31], p = .012), relative to no plaque). Moderation analyses indicated that self-silencing was related to odds of plaque index ≥2 in non-white women (1.15 [1.05-1.26], p = .004), but there was no significant relationship in white women (1.01 [0.97-1.06], p = .550). No associations emerged for IMT.

conclusionsAmong midlife women, self-silencing was associated with carotid plaque, independent of CVD risk factors, depression, and health behaviors. Emotional expression in relationships may be important for women's cardiovascular health.

Indexed as

Carotid Artery DiseasesPlaque, AtheroscleroticAdultCarotid Intima-Media ThicknessFemaleHumansMiddle AgedRisk FactorsWomen's HealthAtherosclerosisCardiovascular diseasesCarotid plaqueEmotional expressionSelf-silencingWomen

Identifiers

PMID34124743
PMCPMC8887577
OpenAlexW3171119341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.