ArticleBrain, behavior, & immunity - health2021
SARS-CoV-2 RNA detection in cerebrospinal fluid: Presentation of two cases and review of literature.
Article in Brain, behavior, & immunity - health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Expression of SARS-CoV-2 entry receptor ACE2 in human brain and its association with Alzheimer's disease and COVID-19.Molecular psychiatry · 2025Review
- SARS-CoV-2 viral proteins trigger pain via TLR2/4-MyD88 pathway.Frontiers in molecular neuroscience · 2025Article
- TLR2/NF-κB signaling in macrophage/microglia mediated COVID-pain induced by SARS-CoV-2 envelope protein.iScience · 2024Article
- Acute onset psychiatric diseases after SARS-CoV-2 virus infection among pediatric patients.Frontiers in neurology · 2024Article
- Understanding the neurological implications of acute and long COVID using brain organoids.Disease models & mechanisms · 2023Review
- A Case Report of an Atypical Neurological Presentation of COVID-19 in Pregnancy.Anesthesiology and pain medicine · 2023Article
- Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping.Fluids and barriers of the CNS · 2022Article
- Opioid-Use, COVID-19 Infection, and Their Neurological Implications.Frontiers in neurology · 2022Review
- Comments on "CSF-Confirmed SARS-CoV-2 Acute Encephalitis": SARS-CoV-2-Associated Encephalitis Is Autoimmune Rather Than Infectious.Journal of clinical neurology (Seoul, Korea) · 2022Article
- Can SARS-CoV-2 Infection Lead to Neurodegeneration and Parkinson's Disease?Brain sciences · 2021Review
- SARS-CoV-2 infection of the central nervous system in a 14-month-old child: A case report of a complete autopsy.Lancet regional health. Americas · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurological manifestations of SARS-CoV-2 infection are multiple and heterogeneous. However, confirmation of nervous system impairment by viral RNA detection in cerebrospinal fluid (CSF) is uncommon. We report two cases of central nervous system (CNS) involvement with positive real-time reverse-transcriptase polymerase chain reaction (RT-PCR) test in CSF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.